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Hair and nail cells share similar proteins, indicating a common differentiation pathway.

PAI-2 helps in the maturation and protection of hair and nail cells.

Lab-grown nail cells show characteristics similar to natural nail and hair.

The document concludes that stem cells and their environments are crucial for skin and hair health and have potential for medical treatments.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

Notch signalling helps skin cells differentiate and prevents tumors.

Human nails and hair follicles have similar gene activity, especially in the cells that contribute to their growth and development.

Nail stem cells and Wnt signaling are important for fingertip regeneration but not sufficient for regenerating more complex limb structures.

The nail matrix has a reduced immune response, protecting it from autoimmunity.

The conclusion is that teeth, hair, and claws have similar stem cell niches, which are important for growth and repair, and more research is needed on their regulation and potential markers.

Newly found stem cells in horse hooves show promise for treating a hoof disease called laminitis.

Estrogen increases a growth factor in hair cells which might affect hair loss.

Hair and nail changes can indicate health issues, including cancer and side effects from cancer treatments.

Men with a certain type of hair loss often use facial moisturizers, and a specific antibiotic treatment may help another hair condition.

Carbamazepine may cause reversible nail detachment.

Epidermal stem cells create and maintain skin structures like hair and nails through specific signaling pathways and vary by location and function.

A woman had hair loss, nail changes, and skin peeling after a COVID-19 infection, which got better on their own.

Mammals might fail to regenerate not because they lack the right cells, but because of how cells respond to their surroundings, and changing this environment could enhance regeneration.

The document explains various skin conditions and their treatments.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.

The conclusion is that skin and hair patterns are formed by a mix of cell activities, molecular signals, and environmental factors.

Organs like hair follicles can renew themselves in complex ways, adapting to different needs and environments.

Understanding skin structure and development helps diagnose and treat skin disorders.

About 22% of cancer patients had skin-related side effects from chemotherapy, but these were usually not severe enough to halt treatment.

Wounds can regenerate hair in young mice, but this ability declines with age, offering insights for improving tissue regeneration in the elderly.

A WNT10A gene mutation leads to ectodermal dysplasia by disrupting cell growth and differentiation.

Human hair keratins K85 and K35 create unique filament patterns important for early hair formation.

Different combinations of human hair keratins affect how hair fibers form.

R-spondins and their receptors help increase bone growth and may be used to treat bone loss diseases.

Frizzled 3 and Frizzled 6 together control the orientation of mouse hair follicles.