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GlossaryOnychomadesis

shedding or detachment of a nail from its bed

Onychomadesis is the medical term for the shedding or detachment of a nail from its nail bed, often starting at the base of the nail. This condition can be caused by various factors, including trauma, infections, systemic illnesses, or severe stress to the body.

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Twenty Nail Onychomadesis: An Unusual Finding in Cronkhite-Canada Syndrome

research Twenty Nail Onychomadesis: An Unusual Finding in Cronkhite-Canada Syndrome

13 citations, June 2010 in “Journal of The American Academy of Dermatology”

A man with Cronkhite-Canada syndrome had all 20 nails detach but improved with treatment.

Possible Carbamazepine-Induced Reversible Onychomadesis

research Possible Carbamazepine-Induced Reversible Onychomadesis

13 citations, September 1989 in “International Journal of Dermatology”

Carbamazepine may cause reversible nail detachment.

research Onychomadesis: A Rare Adverse Effect in Early-Period Valproic Acid Therapy

2 citations, September 2015 in “Türk pediatri arşivi : İstanbul çocuk kliniği dergisi”

Valproic acid can very rarely cause nail separation, which usually gets better on its own after stopping the drug.

Propylthiouracil-Induced Alopecia Accompanying Hypohidrosis and Onychomadesis

research Propylthiouracil-Induced Alopecia Accompanying Hypohidrosis and Onychomadesis

August 2022 in “Acta dermato-venereologica”

Propylthiouracil can cause hair loss, reduced sweating, and nail issues, but stopping the drug can reverse hair and nail problems.

Onychomadesis Associated with Childhood Hand-Foot-Mouth Disease

research Onychomadesis Associated with Childhood Hand-Foot-Mouth Disease

March 2012 in “Journal of The American Academy of Dermatology”

Hand-foot-mouth disease may cause nail loss in children.

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