1 citations
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October 2018 in “International research journal of pharmacy” This study found that ethanol extract and n-hexane fraction of rampai leaves may stimulate hair growth in rabbits, showing potential as an anti-alopecia treatment.
April 2016 in “Journal of Investigative Dermatology” This study found that gypenosides from Gynostemma pentaphyllum increased procollagen synthesis in vitro and reduced periorbital wrinkles by about 14% in a clinical trial with 24 women.
111 citations
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March 2012 in “Expert Opinion on Drug Delivery” This review discusses the potential use of liposomal formulations to enhance the effectiveness of cosmeceutical delivery through the skin barrier, with no new clinical results reported.
9 citations
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June 2014 in “Nutrition and Cancer” This study found that hydro-alcoholic Eclipta alba extract may have anticancer and multidrug resistance-reversal effects in animal models, suggesting potential as an adjunctive agent in tumor chemotherapy.
This study found that four synthesized thiazolidinone derivatives showed potential anticancer activity against MCF7 and HeLa cell lines, suggesting their further investigation for anticancer drug development.
April 2011 in “한국생물공학회 학술대회” This study found that an anti-atopic lotion containing fucoidan helped heal skin damage in hairless mice with atopic dermatitis by reducing skin thickness and modulating immune responses.
37 citations
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January 2002 in “British journal of dermatology/British journal of dermatology, Supplement” This study found that procyanidin B-2 may promote hair growth by reducing expression and inhibiting translocation of PKC isozymes in murine hair epithelial cells.
April 2026 in “Cosmetics” In this randomized, double-blind, placebo-controlled trial, researchers found that a multi-targeted cosmetic formulation containing TrinogeniX™ significantly increased hair density and thickness in individuals with androgenetic alopecia without adverse effects, suggesting it as a potential safe and effective treatment option.
2 citations
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July 2023 in “Phytotherapy Research” This study found that people taking Serenoa repens for more than 14 days had a higher likelihood of serious adverse reactions, particularly when also using multiple or interacting supplements, although higher SR doses were linked to lower risk.
66 citations
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September 1982 in “Biochemical Pharmacology” This study identified a sulfotransferase activity in rat liver that catalyzes the sulfation of minoxidil, contributing to its delayed hypotensive effects.
34 citations
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February 1993 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” This study found that 4-MA is a potent inhibitor of testosterone 5α-reductase in human tissues, promising potential for treating androgen-dependent skin conditions like male pattern baldness.
August 2019 in “Key engineering materials” This study found that Carthamus tinctorius floret extract, at a concentration of 0.05 mg/mL, significantly inhibited 5α-reductase activity in DU-145 cells more effectively than standard treatments finasteride and dutasteride, with a stable microemulsion formulation enhancing its skin permeation and stability.
12 citations
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November 2012 in “Bulletin of experimental biology and medicine” Taxifolin-based treatments help skin heal after chemical burns.
16 citations
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October 2021 in “Trends in biotechnology” This review discusses the potential of protein-based cosmetics, including keratin-based particles and fusion proteins, to improve hair properties such as strength and shape, but it reports no new clinical results.
24 citations
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March 2024 in “Antioxidants” In this review, researchers reported that cinnamon and ginger supplementation may benefit PCOS patients by improving hormonal status, lipid profiles, obesity, and insulin resistance through oxidative stress and inflammation reduction.
165 citations
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July 1992 in “Annals of Internal Medicine” This editorial discusses the potential health risks of herbal preparations, highlighting a case of hepatotoxicity in a child due to pyrrolizidine alkaloids in a herbal tea; it reports no new results.
11 citations
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June 2023 in “Drug Delivery and Translational Research” In this study, researchers developed and tested a gel containing apocynin-loaded nanoparticles that showed promising results in treating rheumatoid arthritis in rats, suggesting potential for novel topical treatments in inflammatory conditions.
July 2019 in “Majalah Obat Tradisional” This study reported that a 4% water fraction of green tea leaf extract showed the most effective hair growth promotion in rabbits.
This study found that teak leaf extract can be effective in promoting hair growth in males with androgenic alopecia; however, significant variability in steroid 5-alpha reductase inhibitory activity among samples from different geographic origins means quality control is important for consistent therapeutic potential.
December 2022 in “Cosmetics” This study found that a novel nutraceutical supplement improved hair growth and strength in subjects with hair thinning compared to placebo, without reported side effects.
May 2026 in “Revista Ensaios Pioneiros” This study developed and evaluated topical formulations containing 5% minoxidil and 1% rosemary essential oil for androgenetic alopecia treatment, finding them physically and chemically suitable, but noted that further stability tests and clinical trials are needed to confirm therapeutic efficacy and safety.
88 citations
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February 2008 in “Journal of Medicinal Chemistry” Scientists made the first metal-based compounds from a nonsteroidal antiandrogen drug, which showed potential in fighting both hormone-dependent and independent prostate cancer cells.
4 citations
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February 2017 in “Journal of Cutaneous Medicine and Surgery” This study assessed the dermatologic potential of western red cedar, white spruce, birch, balsam poplar, and black spruce used in First Nations medicine, highlighting several active compounds relevant to dermatology, but noted a lack of high-quality evidence in existing research.
61 citations
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June 2022 in “Journal of Controlled Release” This review discusses the advantages, applications, and current trends of dissolving microneedles for drug delivery across various therapeutic areas and reports no new clinical results.
43 citations
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September 2021 in “Nutrients” This review discusses the vast potential uses of persimmon beyond its dietary benefits, including applications in sustainability and new product development, but reports no new clinical outcomes.
69 citations
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October 2014 in “PubMed” This article reviews the various uses and chemical constituents of Rosmarinus officinalis, a common herb used for conditions affecting multiple bodily systems, but presents no new experimental findings.
In this case study, an 80-year-old woman developed lichen planus pigmentosus inversus after receiving multiple intra-articular injections of a homeopathic preparation, suggesting a possible link, though causality remains speculative.
7 citations
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February 2014 in “Talanta” This study developed an advanced HPLC-ESI-ion trap MS(n) method for the structural identification of cyclosporin A analogs CyA and CyC and reported the first MS(n)-aided identification of a new CyA analog.
January 2026 in “Lumbung Farmasi Jurnal Ilmu Kefarmasian” This study found that a topical emulsion containing purified extracts of sidr leaves and roasted candlenut seeds significantly increased hair growth compared to the base and 2% minoxidil, potentially through their antioxidant and anti-inflammatory properties.
2 citations
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January 2021 in “PLANT ARCHIVES” This study explores the development of a liposomal gel containing andrographolide from the plant Andrographis paniculata to potentially improve psoriasis management by enhancing drug delivery and reducing side effects of conventional treatments.