Synergistic Potential of Topical Emulgent Purified Extract of Sidr Leaves (Ziziphus Spina-Christi L.) and Burnt Candlenut (Aleurites Moluccanus L.) as Alopecia Therapy

This study found that a 3:2 combination of pandan leaf and mother-in-law's tongue extracts in hair tonic showed similar hair growth activity as 5% minoxidil after three weeks.

In this study, topical application of 5% minoxidil significantly increased hair follicle density in a mouse model of androgenetic alopecia, as evidenced by a rise in density from 24.00 in the control group to 40.14 in the treatment group.

In this study using New Zealand White rabbits, a nanoemulsion combining candlenut oil and celery powder improved hair growth over 28 days, showing greater hair weight and thickness than both positive and negative controls, suggesting potential as an alopecia treatment.

This case report from this study demonstrates the potential of treating severe alopecia areata with a combination of microneedling, minoxidil, desoximetasone, and methylprednisolone, noting initial hair regrowth after 14 days but emphasizing the need for further research to confirm long-term efficacy and safety.

This study examined the effects of purified Albizia saponaria bark extract on hair growth in rabbits, finding that a 20% concentration of the extract increased hair weight significantly, though it was less effective than minoxidil.