Exploring the Antioxidative Effects of Ginger and Cinnamon: A Comprehensive Review of Evidence and Molecular Mechanisms Involved in Polycystic Ovary Syndrome and Other Oxidative Stress-Related Disorders

This comprehensive review evaluates the antioxidative effects of ginger and cinnamon in managing polycystic ovary syndrome (PCOS) and other oxidative stress-related disorders. The review includes 65 studies and highlights the potential of these herbs as alternative treatments due to their antioxidative and anti-inflammatory properties. Both ginger and cinnamon have shown beneficial effects on lipid profiles, hormone levels, glucose metabolism, and insulin sensitivity in both human and animal studies. Cinnamon has been shown to restore estrous cyclicity and improve insulin sensitivity, while ginger, containing compounds like gingerols, improves hormonal balance and reduces inflammation. The review emphasizes the need for further research to confirm their safety and efficacy, as current evidence supports their use in PCOS management but highlights variations in efficacy at different dosages.