Research Progress on the Natural Products in the Intervention of Myocardial Infarction

    August 2024 in “ Frontiers in Pharmacology
    Qiuting Guo, Jinhui Wang, Caixia Ni, Jiaojiao Pan, Junbo Zou, Yajun Shi, Jing Sun, Xiaofei Zhang, Deng Wang, Fei Luan
    TLDR Natural products may be safer and effective alternatives for managing heart attacks.
    The document reviews the potential of natural products and medicinal plants in treating myocardial infarction (MI), emphasizing their ability to target multiple pathways involved in MI, such as oxidative stress, inflammation, and apoptosis. Compounds like Quercetin, Diosmetin, Astragaloside IV, Curcumin, and Ovothiol-A have shown promise in protecting heart cells and reducing myocardial injury in animal models. The review highlights the need for more research into these natural therapies, which have demonstrated good therapeutic potential and tolerance. However, it notes that while many natural products have been used to treat MI, randomized controlled trials are limited, and further clinical studies are necessary to confirm their efficacy and safety in humans.
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