Perspective Chapter: Repurposing Natural Products to Target COVID-19 – Molecular Targets and New Avenues for Drug Discovery
May 2022
in “
IntechOpen eBooks
”
TLDR Natural products might help treat COVID-19, but current drugs like hydroxychloroquine haven't worked.
The document discussed the exploration of repurposing natural products and their derivatives for treating COVID-19, focusing on targeting host cell machinery and viral proteins to block virus entry or inhibit viral replication. Despite the clinical testing of drugs like hydroxychloroquine, favipiravir, and chloroquine, none showed conclusive efficacy against COVID-19. This led researchers to consider older drugs of natural origin, leveraging their known pharmacology and advanced screening techniques, as potential treatments.