research 3,3-Diphenylpentane Skeleton as a Steroid Skeleton Substitute: Novel Inhibitors of Human 5α-Reductase 1
A new compound effectively inhibits human 5α-reductase 1.
Search
for
Sort by
Research
420-450 / 1000+ results research Self-Consistent Field Theory for the Interactions Between Keratin Intermediate Filaments
Keratin filaments' elasticity is influenced by their terminal domains and surrounding medium.
research Process Development and Crystallization in Oiling-Out System of a Novel Topical Antiandrogen
In 2017, a new method was created to efficiently produce a topical antiandrogen, a compound used to treat excess sebum and acne, with a high yield and purity.
research Finasteride in Hospitalized Adult Males with COVID-19: A Risk Factor for Severity or an Adjunct Treatment - A Randomized Controlled Clinical Trial
Taking finasteride can partially improve oxygen levels in hospitalized male patients over 50 with COVID-19 pneumonia, but it doesn't affect other outcomes like death rate or hospital stay length.
research Suppression of Cutibacterium Acnes-Mediated Inflammatory Reactions by Fibroblast Growth Factor 21 in Skin
FGF21 can help reduce skin inflammation caused by C. acnes.
research Involvement of Neurosteroids in the Control of Hypothalamic-Pituitary-Adrenal Axis Activity in Pregnant Sheep Under Basal and Stressful Conditions
Neurosteroids play a key role in controlling the brain-adrenal gland activity in pregnant sheep, both in normal and stressful situations.
research Serum C-19 Steroid Sulphates in Females with Clinical Hyperandrogenism
Women with hyperandrogenism have higher androgen levels and lower SHBG, which may contribute to conditions like excessive hair growth and early puberty.
research Longer TA Repeat but Not V89L Polymorphisms in the SRD5A2 Gene May Confer Acne Risk in the Chinese Population
Longer TA repeats in the SRD5A2 gene may increase acne risk in Chinese people.
research A Novel Regio-Specific Cyclosporin Hydroxylase Gene Revealed Through the Genome Mining of Pseudonocardia Autotrophica
Scientists found a new gene in a bacterium that can modify an immunosuppressant drug, potentially helping to treat hair loss.
research Hair Growth Promoting Effects of Emodin in Telogenic C57BL/6 Mice
Emodin may help hair grow similarly to minoxidil and could treat baldness.
research Effects of Hair Tonic and Food Including Korean Medicinal Herbs on Hair Growth in an Alopecia Model of C57BL/6 Mice
Korean medicinal herbs in hair tonic and food increased hair growth in mice.
research Acetate Meliorates Depressive-Like Behaviour in a Rat Model of PCOS Through Suppression of HDAC2 Expression and DNA Methylation
Acetate helps reduce depression in rats with PCOS by lowering specific gene expression and DNA changes in the brain.
research Development and Characterization of Cream Containing Nanostructured Lipid Carriers for Hair Split-End Repairing
Nanostructured lipid carriers can effectively repair hair split-ends for over 3 days.
research Sampling Trial Showed S-Equol Supplementation Helped Relieve Menopausal Symptoms
S-equol supplements significantly reduced menopausal symptoms in most women.
research Hair Growth Activity Test in Male Rabbits Using Hair Tonic Containing Ethanol Extract of Nothopanax Scutellarium Leaves
Nothopanax scutellarium extract can effectively promote hair growth in male rabbits.
research The Hair Growth Effect of Polygoni Multiflori Radix Water Extracts in C57BL/6 Mice
Polygoni mulitiflori Radix water extracts promote hair growth and are safer than minoxidil.
research Comprehensive Evaluation of Low-Level Laser Therapy Effectiveness for Treating Hair Loss
Low-level laser therapy effectively treats hair loss and promotes hair growth.
research Carbon, Nitrogen, And Sulfur Elemental And Isotopic Variations In Mouse Hair And Bone Collagen During Short-Term Graded Calorie Restriction
Calorie restriction changes the elemental and isotopic makeup of mouse hair and bone.
research Accelerated Aging of Hair Follicles in Androgenetic Alopecia
Hair follicles in androgenetic alopecia age faster, especially in the front.
research Development and Characterization of Polydeoxyribonucleotide Loaded Chitosan Polyplex for Wound Healing
The chitosan/PDRN polyplex improved wound healing in diabetic rats.
research Influence of NUDT15 Genotyping on Dose Intensity of Thiopurine Administration and Long-Term Clinical Outcomes
Personalized thiopurine dosing based on NUDT15 genotyping can improve long-term outcomes for ulcerative colitis and Crohn's disease patients.
research Single-Cell RNA Sequencing and Proteomic Analysis of Dermal Fibroblasts Cultured From Female Scalp Identifies Significant Alterations in Cell Populations With Age
Aging changes scalp cells, possibly affecting hair health in older women.
research Contact Dermatitis
Various substances, including cosmetic sponges, vein glue, chai tea, skincare products, and medicaments, can cause allergic contact dermatitis, and healthcare workers often react to N95 masks.
research MTORC1 Activity Is Increased in the Skin of Acne Patients and Is Suppressed With Isotretinoin Treatment
Acne patients have higher skin mTORC1 activity, which is reduced by isotretinoin treatment.
research Ethanolic Extract of Ganoderma Lucidum for Androgenic Alopecia Treatment in Testosterone-Induced Bald Rats
Ganoderma lucidum extract promotes hair growth in bald rats, with higher doses producing better results, similar to the effects of Minoxidil 2%.
research Serum Micronutrient Levels in Premature Canities: A Systematic Review and Meta-Analysis
Low levels of vitamin B12, ferritin, and calcium are linked to premature graying of hair.
research Non-Canonical Wnt Signaling Promotes Directed Migration of Intestinal Stem Cells to Sites of Injury
Special gut cells help stem cells move to and fix injured areas by activating a specific signaling pathway.
research Evaluation of Periodontal Health Among Patients With Polycystic Ovarian Syndrome: A Cross-Sectional Study
Women with newly diagnosed PCOS may have worse gum health than those treated for PCOS.
research Study on the Development of the Technology for the Tincture 'Stimufit' for Use in Telogen Alopecia
The "Stimufit" tincture is safe and effective for treating hair loss.
research The Role of Astrotactin2 in Regulating Mammalian Skin Polarity
Astrotactin2 affects hair follicle orientation and skin cell polarity.