TLDR S-equol supplements significantly reduced menopausal symptoms in most women.
The sampling trial assessed the impact of a 12-week S-equol supplementation on menopausal symptoms in perimenopausal and menopausal women. Participants (n = 247) took 10 mg of S-equol daily and reported on symptoms such as hot flashes, night sweats, and sleep disturbances. After 12 weeks, 90% of women noted improvements in one or more symptoms, with 82%, 71%, and 40% reporting improvements in hot flashes, night sweats, and sleep disturbances, respectively. The study concluded that S-equol supplementation significantly alleviated common menopausal symptoms, with over 90% of reported changes being improvements. The study was funded by Pharmavite LLC.
2 citations
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September 2025 in “Cosmetics” Hormonal therapies can improve skin issues by adjusting hormone levels, with future advancements promising better results.
January 2017 in “Springer eBooks” Eating a balanced diet with specific nutrients can help manage menopause symptoms and prevent related health issues.
22 citations
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January 2015 in “The Cochrane library” DHEA may help with sexual function when used intravaginally by menopausal women but is similar to hormone therapy in other aspects and might cause more side effects like acne and hair loss.
14 citations
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April 2022 in “Climacteric” Menopause causes dry skin, wrinkles, and hair changes, with hormone therapy helping but not recommended just for these issues.
November 2022 in “The Journal of Clinical Endocrinology and Metabolism” Postmenopausal hyperandrogenism, a condition with symptoms like increased hair growth and acne, is usually caused by PCOS but can also be due to other factors. It's diagnosed by checking testosterone levels and treated either by removing the adrenal tumor or through antiandrogen therapy.
