Dehydroepiandrosterone for Women in the Peri- or Postmenopausal Phase

    January 2015 in “ The Cochrane library ”
    Carola S. Scheffers, Sarah Armstrong, Astrid E. P. Cantineau, Cindy Farquhar, Jordan
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    TLDR DHEA may help with sexual function when used intravaginally by menopausal women but is similar to hormone therapy in other aspects and might cause more side effects like acne and hair loss.
    The 2015 review analyzed the impact of dehydroepiandrosterone (DHEA) on peri- or postmenopausal women, focusing on sexual function, quality of life, menopausal symptoms, and side effects compared to hormone therapy (HT). It found that while oral DHEA did not significantly improve sexual function, intravaginal DHEA showed some benefits. There was no significant difference between DHEA and HT in enhancing quality of life or alleviating menopausal symptoms. Side effects such as acne and hair loss were more common with DHEA than HT, but these findings were not statistically significant. The review suggests that intravaginal DHEA might be beneficial for sexual function, but in other respects, it is comparable to HT and may increase the risk of certain side effects.
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