Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study found that adrenal hormones appear to inhibit winter fur growth onset in mink and may affect the duration of inactivity between fur growth periods.

This study observed that processing techniques such as degreasing, bating, and tanning influence mink skin by altering the distribution of fat glands and collagen fibers, potentially impacting hair follicle structure and mink product quality.

This paper highlights advances in Developmental Dynamics, noting how epoa-deficient zebrafish can model Diamond-Blackfan anemia like disorders for drug screening, Alx4 mouse models offer insights into craniofacial development, and mTORC1 signaling is crucial for retinal development.

This study found that nanostructured lipid carriers significantly improved the targeted delivery of latanoprost and minoxidil to pilosebaceous units in porcine skin, with latanoprost showing notably higher accumulation.

This case report describes a 37-year-old female with systemic lupus erythematosus who developed multiple eruptive dermatofibromas; lesions spontaneously resolved and highlight the rare coexistence of these conditions.

This study identified ISX9 as a novel agonist of the Wnt/β‐catenin pathway, which promoted hair regrowth in mice and may offer a therapeutic approach for alopecia.

This preclinical study found that a machine-learning-driven strategy for fabricating microneedles with optimal hardness and rapid dissolution significantly promoted hair regrowth in androgenetic alopecia mice by activating the Wnt/β-catenin pathway, surpassing the effects of minoxidil.

This case report describes an eight-year-old Kashmiri boy diagnosed with monilethrix, a rare genetic hair disorder, characterized by a beaded appearance and fragility of the hair shaft.

In AGA mouse models, this study found that the combination of nickel–copper nanozymes and minoxidil in dissolvable microneedles significantly enhanced hair regeneration and improved the hair follicle microenvironment by reducing reactive oxygen species and increasing vascular density, compared to minoxidil alone.

This study developed and validated a simple, accurate, and sensitive HPTLC method for estimating minoxidil and aminexil in topical solutions, demonstrating effective separation and linear measurement of these compounds with %RSD under 2% and high regression coefficients.

This study found that α-melanocyte-stimulating hormone may modulate inflammation in skin connective tissue by inhibiting proinflammatory effects in fibroblasts.

This study observed that MAA beads improved vascularization in non-diabetic male mice by modulating the Shh signaling pathway in wound granulation tissue, but showed no such effects in females.

In this study, PDLLA treatment in middle-aged mice was observed to enhance hair growth by increasing macrophage M2 polarization and hair follicle stem cell proliferation, potentially rejuvenating the skin's microenvironment and offering a novel approach for age-related hair loss.

Stopping methotrexate might reverse lymphoma-like conditions in some patients.

This case report describes a 10-year-old girl with monilethrix, detailing hereditary autosomal dominant traits and distinctive nodular hair shaft abnormalities observed in her family through clinical examination and microscopic analysis.

This study found that deleting the Mof gene in mouse skin leads to severe defects in skin cell self-renewal, differentiation, and hair follicle growth, indicating that MOF is crucial for mitochondrial and ciliary gene expression and essential for skin development.

This study found that Sox2 within dermal papilla cells in the hair follicle regulates hair pigmentation, influencing the type and production of melanin.

This study demonstrated that ablation of individual somatostatin-expressing interneurons increased activity in nearby neurons of the mouse motor cortex during motor learning.

This study found that modulating BMP activity in transgenic mice affects the development and characteristics of several ectodermal organs, such as skin, hair, and claws, highlighting a stage-dependent influence on organogenesis.

QMSI effectively maps and quantifies drug distribution in skin tissues.

This study developed lipid-core nanocapsules for encapsulating menthol, improving its solubility and thermal stability, and demonstrated their safety and rapid skin absorption in ex vivo tests, highlighting potential applications for cosmeceuticals.

Hox genes control hair follicle stem cell regeneration in different body regions.

This study discusses a potential new treatment called AMPLEX PLUS that may significantly slow hair loss and stimulate new hair growth by influencing the transition of hair follicles from the telogen phase to the active anagen phase.

This study investigated differences in gene expression in the mammary glands of SLICK and wild-type Holstein cattle, finding limited differences overall but identifying enriched pathways related to arachidonic acid metabolism and oxytocin production, which merit further exploration.

This study reported that a magneto-responsive transdermal microneedle system delivered Minoxidil effectively and significantly increased hair density by 800% in mice with androgenetic alopecia after 10 days.

In this study, topical 5% roxithromycin was effective in restoring hair growth in about half of individuals with androgenetic alopecia without causing adverse effects.

This study identified a 582-bp deletion upstream of LHX2 in cashmere goats, likely linked to hair follicle development and cashmere production, providing insights into genetic factors in cashmere trait selection.

This study identified key cells and pathways needed for the development of touch receptor patterns in mouse skin, notably that certain keratinocytes are crucial for innervation patterns, while Merkel cells and BMP signaling have distinct roles.

In this study, researchers used a murine model of irritant contact dermatitis to reveal that hair follicle regions serve as key sites for neutrophil transepidermal migration, which requires MMP-9 expression stimulated by dermal monocytes.

This case report on a 13-year-old boy with monilethrix observed slight improvement after a two-month trial of oral N-acetyl cysteine, but overall hair density did not improve further.