The Crosstalk of Monocyte-Neutrophil in Hair Follicles Regulates Neutrophil Transepidermal Migration in Contact Dermatitis

    April 2025 in “ Communications Biology
    Zhan Fan, Yilun Xu, Yafang Lu, Xinlin Li, Mengli Xu, Jinxin Liu, Zhenzhen Cai, Jiayang Liu, Jingping Su, Jialu Wang, Qingming Luo, Zhihong Zhang, Zheng Liu
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    Studysummary In this study, researchers used a murine model of irritant contact dermatitis to reveal that hair follicle regions serve as key sites for neutrophil transepidermal migration, which requires MMP-9 expression stimulated by dermal monocytes.
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