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This systematic review synthesizes evidence from the past 20 years to highlight the potential of exosome-based therapies from stem cells and plants in improving cutaneous repair, skin aging, and challenging dermatological conditions through mechanisms like immunomodulation and collagen remodeling.

In this study, a chronotherapeutic bilayer dressing system showed enhanced diabetic wound healing in a model by reducing inflammation through polyphenols and promoting repair with sustained PDGF-BB delivery, leading to faster re-epithelialization and hair follicle regeneration.

This review explores the skin benefits of exercise and discusses how artificial intelligence can tailor exercise programs to individual skin health needs, emphasizing the potential of AI-driven strategies in cosmetic dermatology for more personalized and adaptive skincare approaches.

This study identified key proteins, FKBP10 and FBN2, that promote the growth cycle of secondary hair follicles in cashmere goats, with higher expression in the anagen phase, offering insights into mechanisms potentially enhancing cashmere yield and quality.

In this review, it is discussed how mesenchymal stem cell aggregation plays a crucial role in organ development and has potential applications in organ regeneration through tissue engineering.

In this study, researchers found that supramolecular peptide self-assembling materials derived from Pacific oysters exhibit promising effects for skin wound healing in vitro and in vivo, demonstrating procoagulant, antioxidant, anti-inflammatory, and regenerative properties that suggest potential as a natural treatment option.

This chapter reviews the potential of stem cells from discarded deciduous teeth in regenerative medicine and dentistry, with no new clinical results presented.

This article reviews the clinical use of platelet rich plasma for skin regeneration, highlighting the challenges of inconsistent outcomes due to varying preparation protocols, and calls for standardized models to better assess its effectiveness.

This study reviews advancements in the use of biodegradable polymers for wound healing, highlighting various polymer formulations and the observed enhancement of processes like cell proliferation and wound healing in both in-vitro and in-vivo experiments.

Various treatments can improve post-acne scars, but results vary.

This review explores the potential of multifunctional bioscaffolds in skin tissue engineering, highlighting their successful biological performance in vitro and in vivo animal models, while also identifying the demand for technological advancements to improve wound healing applications in clinical settings.

This review discusses various tissue engineering approaches for hair follicle regeneration and biomaterials used, emphasizing its potential despite current clinical challenges.

This review discusses recent advancements in nanotechnology-based treatments for chronic wound healing in diabetic models, noting that despite promising results, these innovations have yet to translate into widely available commercial products.

In this study, a novel electrospun dressing patch made with radially oriented PHBV nanofibers and loaded with berberine was shown to significantly accelerate diabetic wound healing in mice, achieving 100% wound closure in 18 days while also demonstrating improved mechanical and anti-inflammatory properties.

This review discusses the roles and mechanisms of Wnt signaling in embryonic and adult stem cells and its association with cancers, and reports no new experimental findings.

This article reviews the therapeutic use of interferons and other cytokines in various viral, tumorous, and inflammatory diseases, discussing their biological effects and potential future applications without presenting new experimental results.

This ex vivo study reported that melatonin significantly improved certain aging biomarkers in aged human skin, including reduced mTORC1 activity, increased fibrillin-1, and enhanced collagen and elastic fiber organization, though other key biomarkers remained unchanged.

In this review, researchers reported that incorporating nanoparticles into natural-based biomaterials enhanced scaffolding properties, cellular interactions, and outcomes in wound healing, with promising implications for tissue engineering and regenerative medicine, although many signaling pathways involved are still not fully understood.

This study found that nanofibers combining a polydopamine coating and curcumin nanocrystals were effective in treating diabetic wounds infected with methicillin-resistant Staphylococcus aureus by providing sequential photothermal antibacterial action and promoting M2 macrophage polarization, which accelerated wound healing through enhanced angiogenesis and cell proliferation.

This study reports that the mechanical interactions between human skin and adjacent subcutaneous white adipose tissue influence the appearance of skin wrinkles, with sWAT reinforcement potentially more effective for reducing signs of skin aging than skin reinforcement alone.

This review discusses plant-based alternatives to retinoids for dermal antiaging and hair health, highlighting roles for cytokinins and phytoestrogens and reports no new results.

This symposium reviewed various advances in understanding and potentially reversing skin aging, with no new experimental results reported.

This review highlights the challenges in developing nano-scale drug delivery systems for natural antioxidants in wound healing, pointing out issues like low solubility and skin permeability, and discusses potential solutions such as combining polymers and lipids to enhance delivery effectiveness.

This study in an animal model found that Rigenera® technology's use of autologous micrografts improved wound healing in diabetic rats by increasing factors like VEGF-A, IL4, and IL10 while reducing TNF-α and oxidative stress.

This study found that adding epidermal growth factor to mesenchymal stem cells enhanced wound healing and hair follicle regeneration in rats compared to stem cells alone.

This review examines the potential and challenges of extracellular vesicles in cosmetics, noting their transformative impact despite regulatory and production hurdles; it reports no new experimental results.

The researchers reported that marine-derived saccharides, specifically L-fucose and chondroitin sulphate disaccharide, supported skin and hair health by promoting cellular proliferation, enhancing extracellular matrix production, and aiding the hair cycle's growth phase, potentially minimizing aging effects.

This study suggests that the synthetic peptide SPIKENET (SPK) may protect against long-term skin alterations in mice following coronavirus infection, offering potential therapeutic intervention for similar effects in humans post-COVID-19.

This review summarizes the research on bioactive materials that modulate the skin microenvironment to promote wound healing and highlights the essential role of the fascial layer, without presenting new experimental results.

This study found that fermented red ginseng marc alleviated atopic dermatitis-like symptoms in mice, demonstrating antioxidant and anti-inflammatory effects similar to those of dexamethasone.