Fascia Layer - A Novel Target for the Application of Biomaterials in Skin Wound Healing

    February 2023 in “ International Journal of Molecular Sciences ”
    Haifeng Ye, Yuval Rinkevich
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    TLDR The fascial layer is a promising new target for wound healing treatments using biomaterials.
    The paper "Fascia Layer—A Novel Target for the Application of Biomaterials in Skin Wound Healing" discusses the significant role of the fascial layer, a connective tissue beneath the skin, in wound healing and repair. The authors suggest that bioactive materials, such as nanocomposite dressings, aloe/chitosan nanohydrogels, and silver nanoparticle-laden collagen/chitosan scaffolds, can modulate the skin's microenvironment and cell behavior, facilitating wound repair and skin attachment regeneration. The paper also introduces the fascia layer as a new target for these biomaterials. The authors also discuss the potential of scaffolds in skin tissue engineering, each with its own advantages and disadvantages. The paper concludes that the fascial layer could provide a new target for clinical wound healing treatment.
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