TLDR PRP helps skin regeneration but needs standardized testing for consistent results.
The review evaluates the effectiveness of platelet-rich plasma (PRP) in skin regeneration, concluding that PRP shows promising results in enhancing skin healing and rejuvenation by improving skin texture, elasticity, and overall appearance through collagen production and cellular regeneration. However, the review emphasizes the need for standardized protocols and larger, more rigorous studies to confirm these findings and establish optimal treatment parameters. It also suggests that standardized experimental models, such as ex-vivo human full-thickness skin culture models, are crucial for objectively demonstrating PRP's effectiveness.
58 citations,
January 2020 in “International Journal of Molecular Sciences” Different methods of preparing Platelet-Rich Plasma (PRP) can affect wound healing and hair regrowth in plastic surgery. Using a kit with specific standards helps isolate PRP that meets quality criteria. Non-Activated PRP and Activated PRP have varying effects depending on the tissue and condition treated. For hair regrowth, Non-Activated PRP increased hair density more than Activated PRP. Both treatments improved various aspects of scalp health.
176 citations,
June 2019 in “Cells” Different fibroblasts play key roles in skin healing and scarring.
76 citations,
December 2018 in “Aesthetic Plastic Surgery” Platelet-rich plasma may help in skin and hair treatments, and with muscle and joint healing, but more research is needed to fully understand its benefits and limitations.
49 citations,
August 2016 in “Aesthetic Surgery Journal” Micro-needling effectively improves wrinkles, scars, and hair growth, but proper technique and safety are important.
March 2024 in “Biomedicines” Mesenchymal stem cells show promise for effective skin repair and regeneration.
9 citations,
November 2018 in “Drug Discovery Today” Using skin stem cells and certain molecules might lead to scar-free skin healing.
133 citations,
July 2020 in “Cells” Creating fully functional artificial skin for chronic wounds is still very challenging.
18 citations,
August 2018 in “Facial Plastic Surgery Clinics of North America” Lasers, microneedling, and PRP improve skin rejuvenation and repair, with PRP enhancing the effects when combined with other treatments.
76 citations,
February 2021 in “International Journal of Molecular Sciences” Mesenchymal stem cells show potential for skin healing and anti-aging, but more research is needed for safe use, especially regarding stem cells from induced pluripotent sources.
