Melatonin Exerts Prominent, Differential Epidermal and Dermal Anti-Aging Properties in Aged Human Eyelid Skin Ex Vivo

    November 2023 in “ International Journal of Molecular Sciences ”
    Tara Samra, T. Gomez-Gomez, Kinga Linowiecka … Ralf Paus
    Studysummary This ex vivo study reported that melatonin significantly improved certain aging biomarkers in aged human skin, including reduced mTORC1 activity, increased fibrillin-1, and enhanced collagen and elastic fiber organization, though other key biomarkers remained unchanged.
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