Marine-Derived Bioactive Peptides in Self-Assembled Multifunctional Materials: Antioxidant and Wound Healing Properties

    May 2023 in “ Antioxidants ”
    Dingyi Yu, Shenghao Cui, Liqi Chen, Shuang Zheng, Di Zhao, Xinyu Yin, Faming Yang, Jingdi Chen
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    TLDR Peptides from oysters may safely and effectively heal skin wounds with less scarring.
    The document discusses a study on the wound healing properties of peptide self-assembling materials (CAPs) derived from the Pacific oyster (Crassostrea gigas). The study involved both in vitro and in vivo experiments. In vitro tests showed that CAPs have antioxidant activity, promote coagulation, and enhance cell proliferation. In vivo tests on mice showed that CAPs can reduce inflammation, stimulate fibroblast proliferation, promote revascularization, accelerate the epithelialization process, and promote hair follicle regeneration. The study also observed a balanced collagen I/III ratio in the repaired tissue, indicating a potential for reducing scarring. The study concluded that CAPs could be a natural, safe, and effective treatment for skin wound healing, with potential for further development in traceless skin wound healing.
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