Oral Delivery of Marine Shellfish Supramolecule Peptides for Skin Wound Healing

In this study, researchers found that supramolecular peptide self-assembling materials derived from Pacific oysters exhibit promising effects for skin wound healing in vitro and in vivo, demonstrating procoagulant, antioxidant, anti-inflammatory, and regenerative properties that suggest potential as a natural treatment option.

This study found that multifunctional peptide-based materials derived from Crassostrea gigas may promote scarless dermal wound healing without affecting intestinal flora through both topical and oral administration.

This study found that fish scale collagen peptide significantly promoted wound healing in mice, with the <1 kDa fractions enhancing collagen synthesis and reducing inflammation, suggesting potential clinical benefits.

This review highlights the promising biomedical applications of marine-derived polysaccharides, proteins, and peptides, particularly in drug delivery and wound healing. It discusses their potential as biomaterials in creating nanocarriers, hydrogels, and more, alongside fabrication strategies, regulatory challenges, and sustainability considerations.

This study developed multifunctional nanofiber wound dressings that significantly reduced bacteria and promoted healing in a mouse wound model by incorporating antibacterial and growth-promoting agents.