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Microneedle technology has advanced for painless drug delivery and sensitive detection but faces a gap between experimental use and clinical needs.

Retinoids can prevent skin cancer in high-risk people but have side effects and require more research on dosing and effectiveness.

The document concludes that early diagnosis and a comprehensive treatment plan are crucial for managing hair loss in children, with a focus on both medical and psychological support.

Mimicking growth factors in a topical solution can prolong hair growth phase and reduce hair loss without side effects.

Isotretinoin is highly effective in treating severe acne, rosacea, and gram-negative folliculitis.

Systemic retinoids are effective for psoriasis but have side effects; benefits may outweigh risks, especially when reducing cancer risks from other treatments.

PRP therapy helps skin heal and improve by promoting cell growth and repair.

Keratin proteins are increasingly recognized as important for cell health and are linked to many diseases.

Non-coding RNAs could help detect and treat radiation damage.

The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.

A boy's skin fragility and sparse hair were caused by a genetic mutation affecting skin cell adhesion.

Overexpression of sPLA2-IIA in mouse skin reduces hair stem cells and increases cell differentiation through JNK/c-Jun pathway activation.

Stress may contribute to hair loss in alopecia areata by affecting immune responses and cell death in hair follicles.

Fibroblast Growth Factors (FGFs) are important for tissue repair and regeneration, influencing cell behavior and other factors involved in healing, and are crucial in processes like wound healing, bone repair, and hair growth.

Certain mouse strains develop a skin condition similar to a human hair loss disease due to genetic defects.

Skin-derived stem cells grow faster and are easier to obtain than hair follicle stem cells, but both can become various cell types.

Mesenchymal stem cells show promise for treating various skin conditions and may help regenerate hair.

Creating fully functional artificial skin for chronic wounds is still very challenging.

Giving a special protein to dogs with a certain genetic disease improved their symptoms but didn't help with hair growth.

Skin grafting and wound treatment have improved, but we need more research to better understand wound healing and create more effective treatments.

Actinic keratosis can lead to skin cancer, is more common in fair-skinned people, and can be reduced with sunscreen and treated effectively.

PTEN helps control the number and health of skin stem cells by working with the protein BMAL1.

The study created hair-bearing skin models that lack a key protein for skin layer attachment, limiting their use for certain skin disease research.

Thymic stromal lymphopoietin (TSLP) promotes hair growth, especially after skin injury.

Cepharanthine has many medicinal uses but needs improvement for better effectiveness.

Special proteins are important for skin balance, healing, and aging, and affect skin stem cells.

Many hospitalized children with COVID-19 had skin, mouth, or nail changes, with skin rashes being common.

Epithelial stem cells are crucial for tissue renewal and repair, and understanding them could improve treatments for damage and cancer.

An imbalanced gut and lack of biotin can cause hair loss in mice.

Circadian clock genes are important for hair growth and may affect aging-related hair loss and graying.