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Targeting colon cancer stem cells might lead to better treatment results.

Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.

Targeted cancer therapies often cause serious skin problems that need careful management.

Dermatoscopy and videodermatoscopy are useful for diagnosing and monitoring various skin, hair, and nail conditions.

Memory T cells in the skin balance staying put and moving into the blood, clustering around hair follicles, and increasing in number after infection.

Adam10 enzyme is crucial for healthy skin and proper Notch signaling.

Targeted cancer therapies often cause skin reactions, so dermatologists must manage these effects.

Certain types of T cells are essential for healthy skin and play a role in skin diseases, but more research is needed to improve treatments.

Skin reactions to antidepressants are common but usually not serious and can be treated.

Syphilis has a wide range of symptoms that can look like other diseases, and if not treated, it can progress to a more serious stage, especially in HIV-positive patients.

The research suggests that Tourette syndrome is linked to both brain signaling and immune system pathways.

EGFR cancer drugs often cause a rash, which can lead to distress and isolation, but may also improve outcomes for some cancer patients. Current treatments for the rash are limited, but a compound called menadione shows promise.

Reflectance confocal microscopy can help tell apart scarring from non-scarring hair loss.

Scalp involvement is common in pemphigus and can lead to hair loss, with the severity of scalp lesions linked to overall disease severity.

Dermoscopy is useful for many health professionals, not just dermatologists, in improving skin condition diagnoses and reducing unnecessary biopsies.

New drugs targeting DNA enzymes show promise for cancer treatment but have side effects like immune system suppression and hair loss.

HIV can cause skin disorders, which are often the first sign of infection, especially in people with darker skin.

A patient with Cronkhite-Canada Syndrome developed colon cancer that spread to the liver, showing the need for regular cancer checks in such patients.

Hormone imbalances from endocrine diseases can cause various skin conditions that help diagnose and treat these diseases early.

Ruxolitinib significantly improves multiple autoimmune conditions in APS-1 patients.

Albendazole can cause hair loss, and piroxicam can cause fixed drug eruption.

Uncombable hair syndrome causes frizzy hair and can affect the nervous system, eyes, and ears, often co-occurring with other hair, skin, nail, and teeth conditions, and is linked to three specific gene mutations.

Wild African goats have genetic adaptations for surviving harsh desert conditions.

The April 2016 JEADV issue covered various dermatology topics, including psoriasis, psoriatic arthritis, mTOR inhibitors, autoimmune diseases, photodynamic therapy, viral DNA in skin diseases, chronic hand eczema, and female hair loss.

Some skin conditions are associated with other serious diseases, and office microscopy may miss many fungal infections.

A thorough skin history and examination are essential for diagnosing and treating skin conditions effectively.

Retinoids are effective for skin conditions like severe acne and psoriasis but must be used with caution due to potential side effects and risks during pregnancy.

Skin changes can help diagnose and manage endocrine disorders like thyroid problems, diabetes, and adrenal gland conditions.

CRTH2 antagonists might be useful for treating many conditions because they play a role in immune and inflammation responses.

Skin health and repair depend on the signals between skin stem cells and their surrounding cells.