research Genome-Wide Gene Expression Dataset Used to Identify Potential Therapeutic Targets in Androgenetic Alopecia
Five molecular elements identified as potential future targets for hair loss therapy.
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690-720 / 1000+ results research Molecular Mechanisms Regulating Hair Follicle Development
Understanding hair follicle development can help treat hair loss, skin regeneration, and certain skin cancers.
research A Composite Model for the Transport of Hydrophilic and Lipophilic Compounds Across the Skin: Steady-State Behavior
The model better predicts how water-loving and fat-loving substances move through the skin by including tiny pores and hair follicle paths.
research Culture of the Human Pilosebaceous Unit, Hair Follicle, and Sebaceous Gland
The article concludes that developing in vitro models for human hair structures is important for research and reducing animal testing, but there are challenges like obtaining suitable samples and the models' limitations.
research A New Humanized Mouse Model For Alopecia Areata
A new mouse model helps understand and find treatments for alopecia areata.
research Molecular Characterization of HOXC8 Gene and Methylation Status Analysis of Its Exon 1 Associated with the Length of Cashmere Fiber in Liaoning Cashmere Goat
The methylation of the HOXC8 gene's exon 1 affects cashmere fiber length in goats.
research Molecular Characterization, Expression and Methylation Status Analysis of BMP4 Gene in Skin Tissue of Liaoning Cashmere Goat During Hair Follicle Cycle
BMP4 gene is crucial for hair follicle development in Liaoning cashmere goats.
research Transgenic Flash Mice for In Vivo Quantitative Monitoring of Canonical Wnt Signaling to Track Hair Follicle Cycle Dynamics
Researchers developed a mouse model that tracks hair growth using bioluminescence, improving accuracy in studying hair cycles.
research Molecular Basis of Androgenetic Alopecia
research Biomechanics of Hair Fiber Growth: A Multi-Scale Modeling Approach
The model shows that factors like follicle shape and stiffness are key for hair growth and anchoring.
research Advances in Molecular Pathogenesis of Hidradenitis Suppurativa: Dysregulated Keratins and ECM Signaling
Recent findings suggest that genetic factors, immune system issues, and skin cell defects might contribute to the development of hidradenitis suppurativa.
research A General Mathematical Model for the In Vitro Assembly Dynamics of Intermediate Filament Proteins
The model shows that filament flexibility and amino acid differences affect how fast intermediate filament proteins assemble.
research Microscopy-Guided Laser Ablation for the Creation of Complex Skin Models with Folliculoid Appendages
Researchers used a laser to create advanced skin models with hair-like structures.
research Developmental Plasticity of Patterned and Regenerating Oral Organs
Fish teeth and taste bud densities are linked and can change between types due to shared genetic and molecular factors.
research Active Anti-Alopecia Chemical Identification of Merremia Peltata Leaves and Computational Study Toward Androgen Receptor Using Molecular Docking and Molecular Dynamic Simulation
Merremia peltata leaf extract, particularly the bufotalinin compound, shows potential for treating hair loss.
research Anti-Alopecia Activity of Coumarin Derivatives from Merremia Peltata Leaves and Their Binding to Androgen Receptors: A Molecular Study
Scopolin and scopoletin from Merremia peltata leaves may help treat hair loss and showed promising results in rabbit tests.
research Dermatologic Changes in Experimental Model of Long COVID
Mice with a virus similar to COVID-19 had skin damage, but a special treatment helped repair it.
research Molecular and Cellular Characterization of Avian Reticulate Scales and the Evolutionary Development of Skin Appendages in Foot Soles
Bird foot scales develop differently and can repair but not fully regenerate due to the lack of specialized stem cell areas.
research Non-Invasive Monitoring of Low Molecular Weight Biomarkers Relevant to Skin Inflammation and Cancer
Non-invasive methods can effectively monitor skin inflammation and cancer biomarkers.
research Exploring the Mechanisms and Molecular Targets of Taohong Siwu Decoction for the Treatment of Androgenetic Alopecia Based on Network Analysis and Molecular Docking
Taohong Siwu Decoction may help treat hair loss by targeting multiple genes and pathways.
research A Novel 3D Printed Model of Infected Human Hair Follicles to Demonstrate Targeted Delivery of Nanoantibiotics
Nanoencapsulated antibiotics are more effective in treating hair follicle infections than free antibiotics.
research Molecular Heterogeneity of Quiescent Melanocyte Stem Cells Revealed by Single-Cell RNA-Sequencing
Different types of resting melanocyte stem cells have unique characteristics and vary in their potential to become other cells.
research MTurq2-Col4a1 Mouse Model Allows for Live Visualization of Mammalian Basement Membrane Development
The mTurq2-Col4a1 mouse model shows how the basement membrane develops in live mammals.
research Virtual Insights into Natural Compounds as Potential 5α-Reductase Type II Inhibitors: A Structure-Based Screening and Molecular Dynamics Simulation Study
Eriocitrin and silymarin might be effective for hair loss treatment and need more research.
research Oxytocin Receptor Expression in Hair Follicle Stem Cells: A Promising Model for Biological and Therapeutic Discovery in Neuropsychiatric Disorders
Rat hair follicle stem cells have functional oxytocin receptors, useful for studying neuropsychiatric disorders.
research Logic-Based Modeling and Drug Repurposing for the Prediction of Novel Therapeutic Targets and Combination Regimens Against E2F1-Driven Melanoma Progression
Cialis and Finasteride could be repurposed to treat aggressive melanoma.
research Novel Human 3D Skin Model for Skin Aging Research
Scientists created a 3D skin model that shows typical signs of aging, which can help in aging research.
research Molecular Docking of Vitamin D3 Receptor with Potential Herbal Substances as Ligands to Prevent Excessive Hair Loss in Menopausal Women
Certain herbal compounds might help prevent hair loss in menopausal women by activating Vitamin D receptors.
research Development of a Non-Parametric Population Pharmacokinetics Model and Bayesian Estimator for Tacrolimus in Tunisian Renal Transplant Patients
The model and estimator can predict drug exposure in kidney transplant patients well.
research Montagna Symposium 2015: Harnessing Stem Cells to Reveal Novel Skin Biology and Disease Treatments
The symposium showed that stem cells are key for understanding and treating skin diseases and for developing new skin models and therapies.