Active Anti-Alopecia Chemical Identification of Merremia Peltata Leaves and Computational Study Toward Androgen Receptor Using Molecular Docking and Molecular Dynamic Simulation

    August 2022 in “ The Scientific World Journal ”
    Syawal Abdurrahman, Ruslin Ruslin, Aliya Nur Hasanah … Mus Ifaya
    Studysummary This study found that bufotalinin, derived from Merremia peltata leaves, may enhance hair growth by acting as a potential androgen receptor antagonist in rabbits.
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    Research cited in this study 5

    1. Molecular Docking Studies and ADME-Tox Prediction of Phytocompounds from Merremia Peltata as a Potential Anti-Alopecia Treatment Journal of advanced pharmaceutical technology & research · 2021
    2. Annurca Apple Polyphenols Ignite Keratin Production in Hair Follicles by Inhibiting the Pentose Phosphate Pathway and Amino Acid Oxidation Nutrients · 2018
    3. Nature-Derived Lignan Compound VB-1 Exerts Hair Growth-Promoting Effects by Augmenting Wnt/β-Catenin Signaling in Human Dermal Papilla Cells PeerJ · 2018
    4. Diet and Hair Loss: Effects of Nutrient Deficiency and Supplement Use Dermatology practical & conceptual · 2017
    5. Bioassay of Crude Drugs for Hair Growth Promoting Activity in Mice by a New Simple Method Planta Medica · 1980