Molecular Characterization of HOXC8 Gene and Methylation Status Analysis of Its Exon 1 Associated with the Length of Cashmere Fiber in Liaoning Cashmere Goat
January 2017
in “
Genetica
”
TLDR The methylation of the HOXC8 gene's exon 1 affects cashmere fiber length in goats.
The study investigated the HOXC8 gene in Liaoning cashmere goats, focusing on its molecular characterization and the methylation status of its exon 1. Researchers found that the methylation degree of HOXC8 exon 1 in anagen secondary hair follicles was significantly associated with cashmere fiber length, indicating that epigenetic modifications play a crucial role in fiber development. This provided insights into the genetic and epigenetic mechanisms underlying cashmere fiber growth, potentially aiding in improving fiber quality through selective breeding.
