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This study evaluated a menthol-based microemulsion for transdermal delivery of finasteride and silodosin, finding that it enhanced skin permeation and flux compared to aqueous solutions, suggesting a promising method for managing benign prostatic hyperplasia.

In this study, micro-autologous fat transplantation (MAFT) for frontal augmentation using the MAFT-GUN showed high patient satisfaction and no complications among 178 patients, suggesting it may be a reliable method for forehead contouring.

This study found that in a mouse model, betamethasone dipropionate reduced epidermal thickness while fish oil unexpectedly increased it, validating optical coherence tomography as an effective measurement tool.

This study introduces a new method to isolate stem cells from the hair follicle outer root sheath of equine skin, demonstrating that these cells, named eMSCORS, proliferate efficiently and can differentiate similarly to adipose tissue-derived MSCs, offering a promising alternative for equine veterinary applications.

This study introduces an extended approach to the Bonferroni procedure that accounts for correlations among endpoints, aiming to improve test power while maintaining strong control of the family-wise type I error rate in clinical trials.

In this study, electron microscopy of follicular mucinosis showed severe cytoplasmic degeneration in hair follicles, with myelin figures and onion-like lamellar structures, but no indications of mucin release through degeneration or degradation were found.

Two new compounds were found that could promote hair growth as well or better than minoxidil.

This study identified a specific subset of macrophages as a key source of oncostatin M, maintaining hair follicle stem cell quiescence during the resting phase in mice, suggesting a potential target for treating hair disorders.

This study found that women with female pattern hair loss experienced improvements in hair loss severity and quality of life from low-dose oral minoxidil use, despite a common side effect of unwanted hair growth, which most did not consider a reason to stop treatment.

In this study, researchers discovered that the MafB gene, which is important for macrophage differentiation, shows high expression in the pancreas and is influenced by sex steroids, with varied expression patterns in hamster tissues and during reproductive phases.

This study suggests that low-dose oral minoxidil could be a safe and effective option for male and female-patterned hair loss, potentially benefiting those unable to tolerate topical treatments.

This study examined the cardiovascular safety of oral minoxidil, used off-label for androgenetic alopecia, particularly as its usage expands in real-world settings, although specific results were not detailed in the abstract.

This study reports that difluoromethyl nitrile oxide can rapidly functionalize various alkenes at room temperature, leading to products that can transform into valuable medicinal chemistry building blocks like CF2H-isoxazolines for bioactive molecule modification.

In this study, FMN was found to inhibit androgen receptor function and androgen-regulated gene expression in prostate cancer cells, suggesting potential as an antiandrogen therapy.

This study found that OVOL1-regulated genes, particularly Fst and SFRP1, significantly affect the hair-inducing capacity of neonatal mouse dermal cells.

This study reported that using 5% minoxidil topical foam twice daily improved hair density and width in both the frontotemporal and vertex regions of men with moderate androgenetic alopecia.

This study found that introducing rat ornithine transcarbamylase gene into spf-ash mice improved liver and intestinal enzyme activity and normalized some metabolic indicators.

Minoxidil works in liver and outer hair root sheath for hair growth.

The authors reported that 4-O-methylhonokiol decreased TGF-β1-induced cell cycle arrest and oxidative stress markers in human keratinocyte cells, suggesting a potential protective role in TGF-β1-mediated cell cycle regulation.

This letter discusses adverse events related to low-dose oral minoxidil for alopecia, highlighting age-related risks and stressing the importance of contraindication awareness with no new clinical results presented.

In this study, specific SNPs in the FST gene were significantly associated with various wool quality traits in Chinese Merino sheep, suggesting potential markers for breeding programs.

This article summarizes the properties, synthesis, and biomedical applications of molecules with N-oxide functionalities, emphasizing their growing role in healthcare due to their unique properties, such as water solubility and redox reactivity, crucial for drug targeting and cytotoxicity.

In this study, researchers found that minoxidil is compatible with excipients such as Beta-cyclodextrin and cellulose, while it is incompatible with Eudragit S 100 and mannitol, indicating potential formulation challenges in pharmaceutical applications.

This study observed that among a Moroccan population with frontal fibrosing alopecia, common comorbidities included lichen planus pigmentosus (36.8%), rosacea (28.9%), thyroid disorders (23.7%), and dyslipidemia (21.1%), highlighting potential relationships mediated by shared inflammatory or metabolic pathways.

This study introduces a five-modal microscopy technique that allows label-free, in vivo observation and quantitative analysis of various wound healing processes.

In this study, researchers measured the solubility of Minoxidil in supercritical CO₂ under various temperature and pressure conditions and created models to estimate solubility based on different predictive approaches.

This study found that compounded formulations using TrichoSol™ and TrichoFoam™ vehicles for alopecia treatments maintained stability and were effective for use up to 180 days, suggesting these vehicles are suitable for personalizing hair care solutions without significant degradation or physical changes.

This study found that Iraqi women with PCOS who carry the reference wild type alleles of OCT1 had a significant hormonal and metabolic response to metformin, unlike those with mutant alleles.

This study found that hair follicle-derived mesenchymal stem cells can alleviate pyroptosis and improve ulcerative colitis symptoms in mice, suggesting potential new treatments for the condition.

This study investigated the solubility of minoxidil in various solvent mixtures and applied multiple models to understand solute-solvent interactions and energy dynamics.