Ultrastructure of Follicular Mucinosis

The study on the ultrastructure of follicular mucinosis, conducted by Akira Ishibashi and Tomotaka Chujo, used electron microscopy to examine affected hair follicles. It found a disappearance of cell organelles and granular agglutination of cytoplasmic matrices and nuclear chromatin, often linked with tonofilaments. Severe cytoplasmic degeneration was marked by myelin figures and onion-like aggregations of low-electron-density lamellar structures. Although granular substances and collagen fibrils coated with an amorphous material were observed, there was no evidence of mucin release through degeneration or degradation processes.