Combination of Tacalcitol Ointment and Photodynamic Therapy for the Treatment of Follicular Mucinosis of the Scalp

    Roberta Giuffrida, Francesco Borgia, Ilenia Marafioti, Gabriella Riso, Serafinella Patrizia Cannavò
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    TLDR Using tacalcitol ointment with photodynamic therapy may effectively treat follicular mucinosis with scalp hair loss.
    The document presents a case of a 59-year-old female with follicular mucinosis (FM), a rare inflammatory disorder marked by mucin accumulation in hair follicle epithelium, who experienced complete clinical remission of diffuse scalp alopecia following a treatment regimen combining topical tacalcitol ointment and photodynamic therapy. Prior to this case, there was no established standard therapy for FM, and various treatments had been documented. The successful outcome in this case suggests that the combination of tacalcitol and photodynamic therapy may be an effective treatment option for FM with associated scalp alopecia.
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