Label-Free Concurrent 5-Modal Microscopy (Co5M) Resolves Unknown Spatio-Temporal Processes in Wound Healing

September 2021 in “ Communications Biology ”

Markus Seeger, Christoph Dehner, Dominik Jüstel, Vasilis Ntziachristos

wound healing optoacoustic two-photon excitation fluorescence second harmonic generation third harmonic generation brightfield contrast microvascular density collagen density sebaceous gland plasticity vasodilation angiogenesis skin contracture epithelial reformation

Studysummary This study introduces a five-modal microscopy technique that allows label-free, in vivo observation and quantitative analysis of various wound healing processes.

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