research Most Important Skin Diseases of Children: Their Diagnosis and Treatment
Children's skin diseases need special care and treatment.
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research The Role of Moracin M in Promoting Hair Growth: Insights into Mechanisms of WNT/β-Catenin Pathway Activation and Angiogenesis Enhancement in Human Dermal Papilla Cells
Moracin M, a compound from the Moraceae family, has been shown to significantly enhance hair growth by promoting cell proliferation and angiogenesis in human dermal papilla cells (hDPCs). The study found that Moracin M activates the Wnt/β-catenin signaling pathway, leading to increased levels of growth factors such as VEGF, FGF2, KGF, HGF, and MYC, similar to the effects of minoxidil. It also enhances cell migration in human umbilical vein endothelial cells (HUVECs) without cytotoxicity at concentrations up to 50 µM. Additionally, Moracin M increases protein and mRNA levels of VEGF, FGF2, and KGF under inflammatory conditions and stimulates MMP-2 and MMP-9 expression, contributing to wound healing. These results suggest that Moracin M could be a promising alternative to current hair growth treatments.
research The Molecular Anatomy of Cashmere Goat Hair Follicle During Cytodifferentiation Stage
Understanding hair follicle development can help improve cashmere quality.
research Low-Dose Oral Minoxidil Initiation and Monitoring for Hair Loss: A Modified Delphi Consensus of Experts
Experts agree on guidelines for safely using low-dose oral minoxidil to treat hair loss.
research Quantifying the Effects of Repeated Dyeing: Morphological, Mechanical, and Chemical Changes in Human Hair Fibers
Repeated hair dyeing significantly damages hair.
research Morphological and Histological Observations on the Hair Brush of Endoclita Vietnamensis (Lepidoptera, Hepialidae)
The study identifies the pheromone gland's location and structure in Endoclita vietnamensis, aiding future pest control methods.
research A Novel and Safe Modality for Non-Surgical Hair Restoration Using Polydioxanone Monofilament Threads
PDO threads are effective and safe for non-surgical hair restoration.
research A Nonsense Variant In KRT31 Is Associated With Autosomal-Dominant Monilethrix
A variant in the KRT31 gene causes a rare hereditary hair disorder called monilethrix.
research Molecular Docking Study of Phytochemical Compounds from Kushtakudori Ennai as a Potential Anti-Alopecia Treatment
Certain compounds from Kushtakudori ennai may help treat hair loss.
research Differential Association Between Cumulative Dose of 5α-Reductase Inhibitors and Mortality
Higher doses of 5α-reductase inhibitors reduce mortality risk, while lower doses increase suicide risk.
research Nanoemulsion Formulation Combination of Virgin Coconut Oil and Candlenut Oil for Hair Growth in Male White Rats
A 1:3 ratio of virgin coconut oil to candlenut oil is best for promoting hair growth.
research Jagged-1+ Skin Tregs Modulate the Innate Immune Response to Wound Healing
Jagged-1 in skin Tregs is crucial for timely wound healing by recruiting specific immune cells.
research Comparative Trichoscopic Analysis of Efficacy of Combination Therapy Versus Monotherapy of Platelet Rich Plasma and Topical Minoxidil in the Treatment of Androgenetic Alopecia
Combining PRP and minoxidil is more effective for hair loss than using either alone.
research Article Review: Moringa Plant (Moringa Oleifera Lamk.) as a New Candidate for Anti-Acne
Moringa oleifera Lamk. shows promise as an effective anti-acne treatment.
research How to Treat Androgenetic Alopecia – The Most Common Form of Hair Loss: A Review
Androgenetic alopecia can be treated with minoxidil and finasteride, requiring long-term use and patient cooperation.
research Formulation of Hair Tonic Combination of Ethanol Extracts of Moringa Oleifera Lam Leaves and Fragrant Pandan (Pandanus Amaryllifolius Roxb) and Its Activity on Hair Growth in White Rats
The combined extracts of Moringa and Pandan leaves significantly promote hair growth.
research Atomistic Characterization of Healthy and Damaged Hair Surfaces: A Molecular Dynamics Study of Fatty Acids on Protein Layer
Replenishing free 18-MEA can help restore damaged hair surfaces.
research Giant Morpheaform Basal Cell Carcinoma Mimicking Scarring Alopecia: Exception Prone to Neglect
A rare type of skin cancer on the scalp can be mistaken for hair loss, causing delayed diagnosis and severe damage.
research Molecular Docking Studies and ADME-Tox Prediction of Phytocompounds from Punica Granatum Peel as a Potential Anti-Alopecia Treatment
The study investigates the potential of phytocompounds from Punica granatum (pomegranate) peel as an anti-alopecia treatment by targeting the enzyme 5-α-reductase, which is involved in hair loss. Using molecular docking studies, the research identified that lead compounds from the pomegranate peel, specifically Apigenin, Luteolin, and Taxifolin, effectively bind to the 5-α-reductase enzyme with binding energies of -7.15, -7.66, and -7.07 kcal/mol, respectively. These findings suggest that these compounds exhibit strong inhibitory activity against the enzyme, indicating their potential as effective anti-alopecia agents.
research Hair Growth-Promoting Effects of Enz MoriL on Human Dermal Papilla Cells Through Modulation of the Wnt/β-Catenin and JAK-STAT Signaling Pathways
Enz_MoriL from mulberry leaves helps hair growth by affecting specific cell pathways.
research Dose-Response Relationship of Therapeutic Oxygen: More Is Not Necessarily Better and May Be Inferior to No Supplemental Oxygen – Part 2: Implications and Consequences
More oxygen isn't always better and can sometimes be worse.
research Can Plant Extracts Help Prevent Hair Loss or Promote Hair Growth? A Review Comparing Their Therapeutic Efficacies, Phytochemical Components, and Modulatory Targets
Plant extracts can help prevent hair loss and promote hair growth.
research The Impact of Monotherapies for Male Androgenetic Alopecia: A Network Meta-Analysis Study
"Dutasteride 0.5 mg daily is the most effective treatment for male hair loss."
research Iron and Zinc Supplementation in Infancy: Who Benefits the Most? A Randomized Controlled Trial in Indramayu, Indonesia
Iron supplements improved hemoglobin levels and combined iron and zinc reduced measles risk in Indonesian infants.
research Molecular Heterogeneity of Quiescent Melanocyte Stem Cells Revealed by Single-Cell RNA-Sequencing
Different types of resting melanocyte stem cells have unique characteristics and vary in their potential to become other cells.
research Modern Dermatology Brings Treatment Even for Alopecia Areata
Modern treatments can effectively regrow hair and improve life for people with alopecia areata.
research Unveiling the Nuances of Adult Female Acne: A Comprehensive Exploration of Epidemiology, Treatment Modalities, Dermocosmetics, and the Menopausal Influence
Adult female acne is a complex condition that can worsen with menopause, requiring holistic treatment and tailored skincare at different life stages.
research Comparison of Intra-Operative Blood Loss in Patients Undergoing Mono-Polar TURP With and Without Pre-Operative 2 Weeks Use of Finasteride
Taking Finasteride before surgery reduces blood loss and surgery time.
research Most Frequent Dermatoses in Patients with Kidney Transplantation
Kidney transplant patients often have skin issues, mainly infections.
research Investigation of the Cognitive Activity Between the Leaf Extracts of Eclipta Alba and Ziziphus Jujuba in Diabetic Animal Models
Ziziphus jujuba and Eclipta alba leaf extracts improve blood sugar levels and cognitive function in diabetic rats.