12 citations
,
July 1958 in “Journal of Endocrinology” In this animal study, cortisone injections inhibited hair regrowth in rats and rabbits, while bilateral adrenalectomy did not significantly affect the hair regrowth cycle.
11 citations
,
August 2024 in “Nature Communications” In this study, researchers observed that quiescent mouse embryonic fibroblasts showed reduced glycolysis but increased TCA cycle flux and mitochondrial respiration, with these changes linked to metabolic reprogramming involving yes-associated protein inhibition and malate cycle modulation, which supports extracellular matrix protein synthesis.
11 citations
,
January 2016 in “Evidence-based Complementary and Alternative Medicine” This study found that rice bran ash extract and orthosilicic acid both increased melanin synthesis and related protein expression in melanocytes, suggesting potential therapeutic use for melanin deficiency.
11 citations
,
June 2015 in “Scientific Reports” In this study of Han Chinese women, the mitochondrial DNA N haplogroup was associated with a higher risk of late-onset systemic lupus erythematosus and its specific manifestations, such as skin impairment and neurological disturbances.
11 citations
,
October 1997 in “British Journal of Dermatology” This study found that a serum-free culture system supported hair growth from follicles responsive to calcium, glucose, and amino acids, with insulin enhancing the growth, while other factors had no effect.
10 citations
,
April 2020 in “PloS one” This study found that mitochondrial dysfunction due to Crif1 deficiency in hair follicle stem cells significantly slows the hair growth cycle in adult mice but does not impact the maintenance of HFSC populations.
10 citations
,
December 2015 in “Experimental dermatology” This study found that in mice, EGFR activation suppresses mitotic regulators like Rcc2 and Stathmin 1, facilitating the transition to catagen in hair follicles.
9 citations
,
June 2020 in “Korean Journal of Parasitology” This case report describes the first documented instance of sarcoptic mange in a pet rabbit in Korea, with successful treatment using weekly ivermectin injections leading to full recovery.
9 citations
,
February 2019 in “Journal of Clinical Research in Pediatric Endocrinology” In this study, children with classical congenital adrenal hyperplasia were found to have increased epicardial fat thickness, which was associated with subclinical atherosclerosis markers and left ventricular dysfunction, especially in poorly controlled cases.
9 citations
,
January 2015 in “Fundamental & clinical pharmacology” This study found that cyclosporine A's enhancement of hair growth in mice is partly due to its ability to block the nuclear translocation of apoptosis-inducing factor, slowing the hair follicle transition to the catagen phase.
9 citations
,
July 1995 in “Veterinary Clinics of North America: Small Animal Practice” This review discusses causes of hair loss in cats, highlighting self-inflicted trauma due to flea allergy dermatitis, and presents no new clinical findings.
9 citations
,
April 1987 in “International Journal of Dermatology” This article reviews rosacea and rosacea-like demodicidosis, discussing historical findings, but provides no new clinical results; the authors highlight the role of Demodex in related skin conditions.
9 citations
,
April 1970 in “Biochemical pharmacology” This study found that stilbamidine and hydroxystilbamidine can inhibit the release of specific enzymes from lysosomes and mitochondria in rabbit liver at certain concentrations, with effects similar to cortisol and chloroquine.
8 citations
,
July 2024 in “Cells” In this review, researchers explored how PGC-1α might improve aged skin barrier function by influencing mitochondrial function and reducing inflammation, factors that are linked to epidermal health during aging.
8 citations
,
January 2016 This study concluded that replacing the synthetic dye Sunset Yellow with curcumin as a colorant in foods may avoid cytotoxic and genotoxic effects observed in mice.
8 citations
,
February 2013 in “Central European Journal of Biology” This article discusses melanocyte development from neural crest cells and reports no new experimental results; the authors suggest a broader range of functions for melanocytes than previously recognized.
8 citations
,
June 2004 in “Journal of Investigative Dermatology” Certain peptides can prevent hair loss in young rats caused by a cancer drug.
7 citations
,
June 2024 in “Communications Medicine” In this study, researchers analyzed spaceflight data from various sources and found that skin issues during spaceflight are linked to DNA damage, mitochondrial dysregulation, and gene alterations, while also highlighting the skin's adaptability post-flight.
7 citations
,
March 2025 in “Free Radical Biology and Medicine” This study discusses how redox imbalance, specifically through reduced Insulin-like Growth Factor-1 mediated by the transcription factor JunB and sphingolipid metabolism changes, contributes to skin aging by depleting stem cell pools and altering the extracellular matrix, ultimately impacting skin integrity and function.
7 citations
,
March 2023 in “Journal of Investigative Dermatology” Low-intensity ultrasound may help protect hair follicles from chemotherapy-induced hair loss.
7 citations
,
May 2022 in “PLOS ONE” This study found that Hetian sheep with higher wool density produce more and finer wool, with key genes potentially influencing their wool growth and density.
7 citations
,
May 2022 in “Frontiers in Cell and Developmental Biology” This review discusses the molecular mechanisms driving hair follicle degeneration in skin aging and emphasizes the role of the tissue microenvironment on stem cell function, but reports no new research findings.
7 citations
,
July 2016 in “Journal of Biomedical Materials Research Part A” This study found that a novel hydrogel scaffold, cGEL, significantly increased melanin production and melanotic gene expression in human melanocytes compared to other graft materials, suggesting its potential as a superior carrier for skin grafting.
7 citations
,
August 2013 in “Experimental and Therapeutic Medicine” In this study, the researchers optimized a method for culturing melanocyte precursors from hair follicles and found that 1,25-dihydroxyvitamin D3 significantly promotes their differentiation and melanin synthesis.
7 citations
,
January 1976 in “International Journal of Environmental Studies” This study found that applying a mix of cholesterol and Tween 60 detergent to mouse skin significantly reduced epidermal cell mitotic activity.
6 citations
,
September 2023 in “International journal of molecular sciences” This review explores the connection between oxidative stress and polycystic ovary syndrome, discussing potential mechanisms and the possible role of antioxidants; it reports no new clinical results.
6 citations
,
February 2023 in “Cosmetics” This study found that hexane extracts of Nostoc verrucosum significantly inhibited melanin synthesis in melanoma cells and demonstrated antioxidant activity, suggesting potential use in developing cosmetic and functional food products.
6 citations
,
April 2022 in “Biomedicine & pharmacotherapy” This review discusses the potential of using triads of repositioned medicines targeting multiple pathogenic mechanisms to prevent or delay retina degeneration, but reports no new results.
6 citations
,
December 2019 in “Frontiers in genetics” In this study, animal model observations suggested that GLI1 expression may reduce cSCC initiation but is not involved in the tumor's aggressiveness.
6 citations
,
October 2019 in “Jo'jig gonghag gwa jaesaeng uihag/Tissue engineering and regenerative medicine” This study found that rice bran ash extract enhanced melanin biosynthesis-related protein expression in a 3D hair follicle-like tissue model and hair follicle organ culture, suggesting potential for future research in melanogenesis.