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GlossaryMicrovessel Density

number of tiny blood vessels in a specific tissue area

Microvessel Density (MVD) refers to the number of tiny blood vessels, or microvessels, within a specific area of tissue. It is often used as a measure in medical research to assess the extent of angiogenesis, which is the formation of new blood vessels, particularly in the context of tumor growth and other pathological conditions. High MVD can indicate increased blood supply to a tumor, which may correlate with more aggressive disease and poorer prognosis.

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The Effect of Finasteride on the Expression of Vascular Endothelial Growth Factor and Microvessel Density: A Possible Mechanism for Decreased Prostatic Bleeding in Treated Patients

research The Effect of Finasteride on the Expression of Vascular Endothelial Growth Factor and Microvessel Density: A Possible Mechanism for Decreased Prostatic Bleeding in Treated Patients

90 citations, January 2003 in “The Journal of Urology”

Finasteride may reduce prostate bleeding by lowering blood vessel growth factor levels and blood vessel density in certain prostate areas.

research Finasteride Reduces Microvessel Density and Expression of Vascular Endothelial Growth Factor in Renal Tissue of Diabetic Rats

7 citations, June 2015 in “The American Journal of the Medical Sciences”

Finasteride helps reduce blood vessel growth in diabetic rat kidneys.

research Finasteride Inhibits Microvascular Density and VEGF Expression in the Seminal Vesicle of Rats

May 2018 in “PubMed”

Finasteride reduces blood vessel formation in seminal vesicles.

Gelatin-Chondroitin-6-Sulfate-Hyaluronic Acid Scaffold Seeded with Vascular Endothelial Growth Factor 165 Modified Hair Follicle Stem Cells as a Three-Dimensional Skin Substitute

research Gelatin-Chondroitin-6-Sulfate-Hyaluronic Acid Scaffold Seeded with Vascular Endothelial Growth Factor 165 Modified Hair Follicle Stem Cells as a Three-Dimensional Skin Substitute

45 citations, October 2014 in “Stem cell research & therapy”

Modified rat stem cells on a special scaffold improved blood vessel formation and wound healing in skin substitutes.

research Radiation-Induced Microvascular Injury as a Mechanism of Salivary Gland Hypofunction and Potential Target for Radioprotectors

41 citations, July 2016 in “Radiation Research”

Radiation damages salivary glands by harming blood vessels, but antioxidants might help protect them.

research Radiofrequency Treatment Induces Fibroblast Growth Factor 2 Expression and Subsequently Promotes Neocollagenesis and Neoangiogenesis in the Skin Tissue

32 citations, May 2017 in “Lasers in medical science”

Radiofrequency treatment helps rejuvenate skin by boosting collagen and blood vessel growth.

research Should Finasteride Be Routinely Given Preoperatively for TURP?

2 citations, July 2013 in “ISRN Urology (Print)”

Finasteride may reduce bleeding after TURP, but more research needed.

research Vascularization of Skin Substitute Constructed by Vascular Endothelial Growth Factor 165 Gene-Modified Hair Follicle Stem Cells Compounded with Three-Dimensional Gelatin-Chondroitin Sulfate-Hyaluronic Acid

June 2014

The modified stem cells with VEGF165 in a special scaffold improved blood vessel growth and wound healing for skin repair.

Retraction of: Transurethral Resection of Prostate and Bleeding: A Prospective, Randomized, Double-Blind Placebo-Controlled Trial to See the Efficacy of Short-Term Use of Finasteride and Dutasteride on Operative Blood Loss and Prostatic Microvessel Density

research Retraction of: Transurethral Resection of Prostate and Bleeding: A Prospective, Randomized, Double-Blind Placebo-Controlled Trial to See the Efficacy of Short-Term Use of Finasteride and Dutasteride on Operative Blood Loss and Prostatic Microvessel Density

March 2017 in “Journal of endourology”

The journal retracted an article due to inaccurate statistics and asked the authors to revise and resubmit it.

research The Potential of Circulating Endothelial Cells as Prognostic Biomarkers in Prostate Cancer

March 2011 in “European Urology Supplements”

CEC levels may be a useful marker for predicting prostate cancer progression.

research Adverse Effects of Finasteride: Myths and Realities. An Updated Review

8 citations, December 2016 in “Revista Medica De Chile”

Finasteride can cause sexual dysfunction, sperm changes, and affect bone density and metabolism.

research Adipose-Derived Cellular and Cell-Derived Regenerative Therapies in Dermatology and Aesthetic Rejuvenation

60 citations, June 2019 in “Ageing Research Reviews”

Fat from the body can help improve hair growth and scars when used in skin treatments.

research A Comprehensive Review of Platelet-Rich Plasma for the Treatment of Dermatologic Disorders

1 citations, November 2022 in “Journal of Dermatological Treatment”

Platelet-rich plasma can increase hair density and may help treat some skin conditions, but it's costly, not FDA-approved, and needs more research.

research Effects of Finasteride on Vascular Endothelial Growth Factor

35 citations, January 2002 in “Scandinavian Journal of Urology and Nephrology”

Finasteride reduces prostate bleeding by affecting blood vessel growth.

The Combined Use of Platelet-Rich Plasma and Adipose-Derived Mesenchymal Stem Cells Promotes Healing: A Review of Experimental Models and Future Perspectives

research The Combined Use of Platelet-Rich Plasma and Adipose-Derived Mesenchymal Stem Cells Promotes Healing: A Review of Experimental Models and Future Perspectives

4 citations, September 2021 in “Biomolecules”

Using Platelet-Rich Plasma and Adipose-Derived Mesenchymal Stem Cells together can improve healing, including wound healing, bone regeneration, and hair growth.

research Short-Term Cryoprotectant-Free Cryopreservation at −20°C Does Not Affect the Viability and Regenerative Capacity of Nanofat

July 2024 in “Frontiers in Bioengineering and Biotechnology”

Storing nanofat at -20°C for 7 days does not harm its ability to regenerate.

research Expression of Beta-Catenin, p63, and CD34 in Hair Follicles During the Course of Androgenetic Alopecia

4 citations, August 2005 in “Archives of Dermatological Research”

Higher p63 and CD34 levels found in specific scalp areas may affect hair loss progression.

Chronic Telogen Effluvium and Female Pattern Hair Loss Are Separate and Distinct Forms of Alopecia: A Histomorphometric and Immunohistochemical Analysis

research Chronic Telogen Effluvium and Female Pattern Hair Loss Are Separate and Distinct Forms of Alopecia: A Histomorphometric and Immunohistochemical Analysis

8 citations, August 2014 in “Clinical and Experimental Dermatology”

CTE and FPHL are different hair loss types with unique causes.

research Hematuria and Hematospermia Associated with the Use of Finasteride for the Treatment of Androgenic Alopecia: A Case Report

2 citations, October 2017 in “Drug safety - case reports”

Finasteride for hair loss may cause painless bleeding in urine and semen.

$Treatment of Refractory Hematospermia With Finasteride: A Prospective Placebo-Controlled Study$

research Treatment of Refractory Hematospermia With Finasteride: A Prospective Placebo-Controlled Study

October 2023 in “Bangladesh journal of urology”

Finasteride effectively treats hematospermia in 3 months without side effects.

$Finasteride for Treatment of Refractory Hemospermia: Prospective Placebo-Controlled Study$

research Finasteride for Treatment of Refractory Hemospermia: Prospective Placebo-Controlled Study

13 citations, April 2012 in “International Urology and Nephrology”

research Wound Healing: A Cellular Perspective

1160 citations, November 2018 in “Physiological Reviews”

The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

research Control of Hair Growth and Follicle Size by VEGF-Mediated Angiogenesis

520 citations, February 2001 in “Journal of Clinical Investigation”

VEGF helps hair grow and determines follicle size by increasing blood vessel growth.

research Prospect of Stem Cell Conditioned Medium in Regenerative Medicine

298 citations, January 2014 in “BioMed Research International”

Stem cell-derived conditioned medium shows promise for treating various medical conditions but requires standardized production and further validation.

A Randomized Placebo-Controlled Multicenter Study to Evaluate the Safety and Efficacy of Finasteride for Male Chronic Pelvic Pain Syndrome (Category IIIA Chronic Nonbacterial Prostatitis)

research A Randomized Placebo-Controlled Multicenter Study to Evaluate the Safety and Efficacy of Finasteride for Male Chronic Pelvic Pain Syndrome (Category IIIA Chronic Nonbacterial Prostatitis)

127 citations, May 2004 in “PubMed”

Finasteride may help some male chronic pelvic pain patients, but more research needed.

A Prospective, 1-Year Trial Using Saw Palmetto Versus Finasteride in the Treatment of Category III Prostatitis/Chronic Pelvic Pain Syndrome

research A Prospective, 1-Year Trial Using Saw Palmetto Versus Finasteride in the Treatment of Category III Prostatitis/Chronic Pelvic Pain Syndrome

105 citations, January 2004 in “The Journal of Urology”

Finasteride improves chronic pelvic pain, saw palmetto doesn't.

research Pharmacological Therapy of Benign Prostatic Hyperplasia/Lower Urinary Tract Symptoms: An Overview for the Practicing Clinician

98 citations, August 2004 in “BJU international”

Medications have become the main treatment for enlarged prostate symptoms, replacing surgery and watchful waiting.