Finasteride Inhibits Microvascular Density and VEGF Expression in the Seminal Vesicle of Rats

    May 2018 in “ PubMed ”
    Shuai Sun, Yong-Chuan Wang, Kai Guo, Jing Du, Hai-Jun Zhou, An-Ji Ren
    TLDR Finasteride reduces blood vessel formation in seminal vesicles.
    The study investigated the effects of finasteride on microvascular density (MVD) and vascular endothelial growth factor (VEGF) expression in the seminal vesicles of 40 male SD rats. The rats were divided into four groups, with two groups receiving finasteride and two groups serving as controls. Results showed that finasteride significantly reduced the expression of CD34 and VEGF in the seminal vesicles, indicating that finasteride inhibited angiogenesis in this tissue. Specifically, CD34 expression decreased by 6.7% and 15.8% in the finasteride groups compared to controls, and VEGF expression decreased by 6.9% and 14.1%. The study concluded that finasteride can suppress microvessel formation in the seminal vesicles by inhibiting VEGF expression.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 1000+ results

      community Summary of Procapil video by Haircafe

      in Minoxidil  2 upvotes 3 weeks ago
      Procapil is marketed as a natural hair loss treatment but lacks strong evidence and is industry-biased. Minoxidil and Finasteride are the only FDA-approved treatments for androgenetic alopecia.

      community Opinions on Scalp fibrosis and DHT?

      in Research/Science  9 upvotes 3 years ago
      The conversation discusses the theory that scalp fibrosis contributes to male pattern baldness (MPB) by increasing DHT concentration, and mentions treatments like Minoxidil. The user seeks opinions on the theory and the effectiveness of scalp massages.

      community A Different Take on Curing MBP

       16 upvotes 6 years ago
      Addressing hair loss by focusing on posture, blood flow, and craniofacial development. Methods include improving posture, cardiovascular activity, scalp massages, healthy diet, meditation, using minoxidil, and addressing craniofacial issues.

      community Am I crazy or is there a link between being fit and not going bald?

      in Chat 2 weeks ago
      Fit individuals often have full heads of hair, possibly due to lifestyle factors like exercise and diet, while those who are less fit tend to experience more hair loss. Some fit individuals may also use treatments like finasteride and minoxidil to maintain their hair.

    Similar Research

    5 / 1000+ results