TLDR Storing nanofat at -20°C for 7 days does not harm its ability to regenerate.
The study concludes that nanofat can be effectively cryopreserved at −20°C without cryoprotectants for short periods, maintaining its viability and regenerative capacity. This was demonstrated through comparable vascularization, tissue formation, and extracellular matrix composition in wounds treated with either fresh or cryopreserved nanofat. The study involved 8 samples per group and found no significant differences in microvessel and lymph vessel densities, as well as macrophage ratios, between the two groups, suggesting this method is viable for clinical applications.
3 citations,
July 2023 in “Plastic and reconstructive surgery/PSEF CD journals” Nanofat grafting improves scars, rejuvenates skin, and may help hair growth safely, but more research is needed.
8 citations,
June 2023 in “Journal of clinical medicine” Nanofat shows promise for facial rejuvenation and treating skin issues but needs more research for long-term safety.
2 citations,
September 2022 in “Cytotherapy” Fat-derived stem cells show promise for treating skin issues and improving wound healing, but more research is needed to confirm the best way to use them.
70 citations,
February 2021 in “International Journal of Molecular Sciences” Fat-derived stem cells, platelet-rich plasma, and biomaterials show promise for healing chronic skin wounds and improving soft tissue with few side effects.
4 citations,
March 2022 in “Pharmaceutics” Regenerative cellular therapies show promise for treating non-scarring hair loss but need more research.
September 2023 in “International Journal of Trichology” Adipose-derived stem cells may help with hair loss, but more research is needed.
December 2024 in “Cell Communication and Signaling” Fat tissue vesicles protect skin from UV damage better than stem cell vesicles.
