Radiofrequency Treatment Induces Fibroblast Growth Factor 2 Expression and Subsequently Promotes Neocollagenesis and Neoangiogenesis in the Skin Tissue

    May 2017 in “ Lasers in medical science ”
    Patrícia Fróes Meyer, Patrícia Oliveira, Flávia K B A Silva, Ana Clara Santos Costa, Caline R A Pereira, Sebastian Casenave, Rodrigo Marcel Valentim Silva, Luis Gonzaga Araújo-Neto, Sebastião David Santos-Filho, Eric Aizamaque, Hennes Gentil de Araújo, Mário Bernardo-Filho, Maria Goretti Freire de Carvalho, Ciro Dantas Soares
    TLDR Radiofrequency treatment helps rejuvenate skin by boosting collagen and blood vessel growth.
    The study concluded that radiofrequency (RF) treatment effectively induced the expression of fibroblast growth factor 2 (FGF-2), promoting neocollagenesis and neoangiogenesis in skin tissue. RF treatment, with or without hydrolyzed collagen (HC), increased cellularity, intercellular substance accumulation, dermis thickness, microvessel density, and COX-2 levels in Wistar rats. The findings suggested that RF could be a beneficial non-invasive method for skin rejuvenation by enhancing the skin's structural and vascular components.
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