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This study found that radiofrequency treatment, with or without hydrolyzed collagen, increased dermis thickness, neocollagenesis, and FGF2 overexpression in rat skin tissue.

This study compared the microscopic treatment zones created by different fractional lasers and radiofrequency in swine skin, finding distinct patterns and damage levels for each technology.

This study found that fractional bipolar RF energy significantly reduced acne scar severity and improved skin texture, with high subject satisfaction and limited side effects.

In this study, fractional radiofrequency treatment was found to be effective, safe, and well-tolerated for patients with erythematotelangiectatic rosacea, with high satisfaction rates.

In this study, researchers found that negative pressure fractional microneedle radiofrequency significantly improved periorbital wrinkles, hydration, and dermal thickness in patients with periorbital aging, while also increasing orderly collagen and elastic fibers, with minimal adverse effects reported.