January 2010 in “World Clinical Drugs” This study successfully applied an optimized LC-MS/MS method for accurately determining finasteride concentrations and assessing its pharmacokinetics in healthy volunteers.
36 citations
,
June 2019 in “eLife” This study introduces MicrobeFDT, a tool that clusters chemically similar compounds and links them to gut microbial enzymes and toxicities, demonstrating its utility by uncovering previously unknown metabolism of the cancer drug altretamine.
5 citations
,
March 2011 in “Proceedings : 格差センシティブな人間発達科学の創成=Science of human development for restructuring the "gap widening society"” This study introduces a non-invasive photoacoustic imaging technique that accurately measures hair follicle density and subdermal angles, showing strong correlation with the gold-standard photographic method.
January 2005 in “Yaowu fenxi zazhi” This study established a convenient, accurate, and sensitive HPLC-APCI-MS method for determining finasteride in human plasma, suitable for pharmacokinetic studies.
71 citations
,
October 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” This study presents a novel in vitro assay using human folliculoid microspheres to research hair growth, which may facilitate preclinical testing of hair growth-modulatory agents.
9 citations
,
February 2018 in “Journal of The American Academy of Dermatology” This study found that methylene blue staining helped identify late catagen and telogen hair follicles more accurately than unstained follicles, which suggests that established telogen percentage standards may be overestimated.
1 citations
,
November 2003 in “Humana Press eBooks” This article discusses the use of atomic force microscopy for examining human hair surfaces in dermatology, cosmetics, and forensic science, but presents no new research findings.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that using a commercially available IPL home-use device led to significant hair reduction and demonstrated long-term efficacy in maintaining hair reduction one year after treatment.
125 citations
,
March 2017 in “Micromachines” This review highlights recent advancements in microfluidics for 3D tissue model generation and discusses its applications in tissue engineering and high-throughput drug screening without reporting new experimental results.
26 citations
,
June 2016 in “Frontiers in Plant Science” This study describes a method to isolate and analyze young and mature type VI trichomes from wild tomato species using autofluorescence-based cell sorting.
May 2026 in “Drug Delivery” This study introduces a co-design framework using finite element analysis to optimize separable bubble microneedles, demonstrating enhanced transdermal and sublingual drug delivery in preclinical models. In vivo results showed faster hair regrowth and glucose lowering in animals, indicating potential improvements over traditional methods.
Hair properties change under electromagnetic fields and are influenced by individual characteristics and the environment.
2 citations
,
December 2022 in “Bio-Design and Manufacturing” This study demonstrates that the newly developed portable reflectance confocal microscope (PRCM) offers real-time, noninvasive monitoring of wound healing processes by visualizing skin morphology in both mice and humans.
January 2015 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study developed a precise and simple HPLC method for estimating tamsulosin and finasteride simultaneously in pharmaceutical forms, demonstrating good precision and potential usefulness for combined dosage analysis.
In this research, low-fluence light-based hair removal was explored, revealing its potential for at-home use with improvements in efficacy and safety, particularly for dark skin individuals, although further studies are necessary.
3 citations
,
January 2009 in “Eclética Química” This study proposed a simple, rapid permanganometric method for determining minoxidil concentrations in pharmaceutical samples, offering comparable accuracy to chromatographic methods with recovery rates of 94.5 to 95.2%.
2 citations
,
September 2018 in “Journal of Separation Science” This study demonstrated that using finasteride impurity as a non-isotopically labeled internal standard in paper spray ionization–mass spectrometry can effectively and efficiently measure finasteride tablet dissolution, achieving results comparable to high-performance liquid chromatography.
67 citations
,
January 2012 in “Biological and Pharmaceutical Bulletin” This study found that nanoparticles did not permeate intact rat skin but could penetrate skin that had been artificially punctured, primarily through grooves or hair follicles.
May 2024 in “International Journal of Cosmetic Science” This study found that using near-infrared optics, specifically in the second NIR window, allows for effective noninvasive evaluation of intra-hair damage caused by cosmetic treatments, demonstrating distinct damage types and changes in hair condition due to chemical or thermal processes.
58 citations
,
November 2013 in “Journal of Innovative Optical Health Sciences” This review discusses the development and application of multiphoton microscopy in dermatology, highlighting its advantages and potential future research directions without reporting new clinical results.
39 citations
,
January 2015 in “Journal of Electroanalytical Chemistry” In this study, a novel electrochemical sensor using a molecularly imprinted polymer was developed for the sensitive detection of minoxidil, successfully measuring its concentration in real samples.
January 2006 in “The Chinese Journal of Modern Applied Pharmacy” In this study, researchers developed a sensitive HPLC-MS method to measure finasteride in plasma, and found that its pharmacokinetics vary widely among healthy volunteers after taking a 5mg oral dose.
January 2004 in “Chinese Journal of Aesthetic Medicine” This study found that sodium fluoride concentrations inhibited the growth of human hair follicles in vitro, while sodium selenite at a specific concentration mitigated its toxicity.
October 2024 in “Acta Biomaterialia” This study introduced a novel method that uses upright structured illumination microscopy and atomic force microscopy to map the mechanical properties of thick living tissue slices, revealing the intricate mechanical heterogeneity of mouse skin and effects of preservation techniques on tissue stiffness.
6 citations
,
July 2013 in “Molecular Imaging” This study successfully used noninvasive bioluminescence imaging to monitor hair generation in vivo after transplanting hair follicle stem cells in mice.
5 citations
,
January 1997 in “Journal of Occupational Health” The method effectively maps lead and zinc in hair, aiding understanding of heavy metal exposure risks.
22 citations
,
July 2010 in “Drug Testing and Analysis” This study presents a rapid method for detecting multiple xenobiotics in urine, effectively identifying 45 compounds banned in sports with detection limits below WADA's performance levels.
This pilot study employed in-vivo multiphoton microscopy to visualize pigment-producing melanocytes in vitiligo patients, aiming to enhance understanding of treatment impacts and potentially improve transplantation therapies.
1 citations
,
May 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” In this study, researchers developed a custom-designed 3D-printed microscope stage insert for inverted confocal microscopes, enhancing the accessibility of long-term intravital imaging of live cell dynamics in live transgenic mice, particularly in the skin.
January 2021 in “Asian Journal of Pharmaceutical and Clinical Research” This study examined the effectiveness of FT-Raman spectroscopy for detecting polymorphism in Lamivudine and Finasteride, highlighting its advantages over other methods due to its capability to provide sharp, well-resolved spectral bands and reduced sampling issues.