In Vivo Monitoring of Survival and Proliferation of Hair Stem Cells in a Hair Follicle Generation Animal Model

    July 2013 in “ Molecular Imaging ”
    Jung Eun Kim, Byeong‐Cheol Ahn, Ho Won Lee, Mi-Hye Hwang, Sug Kyun Shin, Sang Woo Lee, Young Kwan Sung, Jaetae Lee
    Image of study
    TLDR The technique allowed noninvasive tracking of hair stem cell survival and growth, showing potential for hair loss research.
    In the 2013 study by Kim et al., the researchers used a noninvasive bioluminescence imaging (BLI) technique to track the survival and proliferation of hair follicle stem cells in vivo. They transplanted newborn mouse fibroblasts expressing enhanced firefly luciferase (NF-effluc) into mice and monitored the bioluminescence signals. The luciferase activity in NF-effluc was significantly higher than in untransfected fibroblasts, and the bioluminescence signals decreased over two weeks before plateauing. Hair follicles were confirmed at the implantation site after 14 days, indicating that hair generation by stem cell implantation could be monitored noninvasively. The study demonstrated the potential of this imaging technique for hair loss research and treatment.
    Discuss this study in the Community →

    Research cited in this study

    10 / 10 results

    Related Community Posts Join

    6 / 1000+ results

      community New and Interesting HairLoss Studies/Papers/Reviews

      in Treatment  44 upvotes 4 years ago
      Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

      community Why is it that low testosterone causes hair loss as well? How can I be balding?

      in Chat  158 upvotes 7 months ago
      The conversation discusses the confusion over low testosterone potentially causing hair loss, with users sharing personal experiences and knowledge about hair loss treatments like Finasteride. Some users suggest that hair follicle sensitivity to DHT, not testosterone levels, is the key factor in balding, and others discuss the side effects of hair loss medications.

      community When are we getting a cure to hair loss?

      in Chat 1 year ago
      Potential treatments for hair loss, including Minoxidil, finasteride, RU58841 and various upcoming pharmaceuticals, gene editing and cloning. It is suggested that a cure, if found, would be highly profitable due to the large number of people affected by hair loss globally.

      community Why isn’t anyone talking about this?

      in Research/Science  31 upvotes 9 months ago
      Hair cloning is being developed by companies like Kangstem Biotech and Stemson, with potential availability in a few years. Initial costs are expected to be high, but prices may decrease over time.

      community The theory that explains everything. Please help me make this big!

      in Research/Science  2453 upvotes 3 years ago
      The post and conversation are about the role of the enzyme 3alpha-hydroxysteroid reductase in hair loss and the potential of compounds like procyanidin B2 and sulforaphane to boost its activity for hair regrowth. Further research is needed to develop effective treatments based on this theory.

    Similar Research

    5 / 1000+ results