Measurement of Skin Permeation and Penetration of Nanoparticles for Their Safety Evaluation

    January 2012 in “ Biological and Pharmaceutical Bulletin ”
    Eriko Kimura, Yuichiro Kawano, Hiroaki Todo … Kenji Sugibayashi
    Studysummary This study found that nanoparticles did not permeate intact rat skin but could penetrate skin that had been artificially punctured, primarily through grooves or hair follicles.
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    Research cited in this study 2

    1. 40nm, But Not 750 or 1,500nm, Nanoparticles Enter Epidermal CD1a+ Cells After Transcutaneous Application on Human Skin ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2006
    2. Penetration Profile of Microspheres in Follicular Targeting of Terminal Hair Follicles ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2004