3 citations
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January 2023 in “Journal of Pharmaceutical Negative Results” This study reports that fluconazole emulgel formulations, using jojoba oil and liquid paraffin, showed effective drug release and improved characteristics for treating skin diseases compared to traditional oral formulations.
1 citations
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November 2023 in “Journal of Innovations in Applied Pharmaceutical Science (JIAPS)” In this study, researchers developed a neem oil-based emulgel showcasing anti-dandruff properties with controlled dual release, observing formulation F5 providing a 65.27% release after 8 hours and the highest antifungal inhibition against Candida albicans.
24 citations
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November 2018 in “International Journal of Molecular Sciences” This review discusses ethosomes as lipid carriers that enhance drug penetration into deep skin layers and underscores the need for advanced research on their pharmaceutical applications, but it reports no clinical outcomes.
1 citations
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February 2024 in “Pharmaceutics” This review highlights recent developments in nanovesicular carriers for enhancing molecule delivery into and across the skin, focusing on the design and evolution of phospholipid and non-phospholipid systems used in cosmetics and treating various skin conditions.
1 citations
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July 2022 in “Pakistan biomedical journal” This review discusses ethanol-based transethosome vesicles for drug delivery through the skin, but reports no new clinical results.
25 citations
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July 2019 in “Journal of drug delivery science and technology” This study developed lipid-core nanocapsules for encapsulating menthol, improving its solubility and thermal stability, and demonstrated their safety and rapid skin absorption in ex vivo tests, highlighting potential applications for cosmeceuticals.
2 citations
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January 2016 This study found that nanoemulsions containing oleic acid or eucalyptol significantly enhanced the skin penetration of caffeine and naproxen compared to aqueous solutions, primarily by increasing solute diffusivity in the stratum corneum.
August 2024 in “International Journal of Biological Macromolecules” This study reported that newly developed minoxidil Pickering emulsion gels, designed using cellulose stabilizers, showed promising results for promoting hair regrowth and targeting hair follicles by enhancing the delivery and stabilization properties of the formulation in a hair loss treatment context.
March 2026 in “Pharmaceutics” This review discusses therapeutic deep eutectic solvents as promising "green" solutions for enhancing drug solubility and delivery through the skin, reporting no new clinical results and highlighting future research directions.
14 citations
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July 2007 in “Therapy” This review discusses ethosomes as potential carriers for delivering drugs into deeper skin layers and provides no new clinical results, suggesting a need for further studies on their efficiency in dermal therapies.
March 2023 in “International journal of pharmaceutical sciences review and research” In this study, an Emulgel containing Tridax procumbens extract was formulated and found to have promising physical properties and antimicrobial activity for wound healing.
3 citations
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August 2021 in “Journal of fiber science and technology” This study found that chitin nanofibrils prepared by the aqueous counter collision process exhibited superior emulsifying properties for stabilizing oil droplets in Pickering emulsions compared to cellulose nanofibrils.
November 2024 in “Pharmaciana” This study found that the optimum formula for chia seed oil nanoemulsion hair serum, composed of 33.52% Tween 80 and 46.48% propylene glycol, meets good physical characteristics and stability requirements.
26 citations
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January 2024 in “Gels” This review highlights advancements in nanoemulgel platforms for topical and transdermal drug delivery, noting their improved safety and efficacy over conventional treatments in in vitro and in vivo studies, specifically for conditions like skin diseases and inflammatory issues.
June 2015 in “Biomedical and biopharmaceutical research” This article reviews EU cosmetic product claim regulations and highlights increased harmonization and enforcement while reporting no new results.
105 citations
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April 2017 in “International Journal of Nanomedicine” In this study, ethosomes were found to improve the skin penetration of a model lipophilic drug more effectively than liposomes or hydroethanolic solutions, suggesting a unique mechanism involving the breakdown of vesicles in the skin.
13 citations
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January 2019 in “Colloids and Surfaces B: Biointerfaces” This study found that incorporating a block copolymer significantly alters the size and morphology of niosome drug delivery systems made of non-ionic surfactants and cholesterol, affecting their stability.
29 citations
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June 2014 in “Drug delivery” This study reported that nanoemulsions significantly improved the skin permeability of thiocolchicoside compared to its aqueous solution, suggesting they are effective carriers for its transdermal delivery.
19 citations
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July 2020 in “Journal of drug delivery science and technology” This study found that nano-sized minoxidil formulations significantly increased skin penetration and follicular drug delivery for alopecia areata treatment, compared to conventional ethanol-based solutions, and demonstrated effective controlled release over six hours.
202 citations
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June 2005 in “Aaps Pharmscitech” This review discusses the potential of lecithin organogels for improving topical drug delivery and presents no new experimental results; the authors highlight their stability and low skin irritancy as advantages.
29 citations
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December 2021 in “Pharmaceutics” This review discusses the use of phospholipid soft vesicle carriers to improve the delivery and therapeutic outcomes of topical treatments for various skin conditions, but reports no new clinical results.
April 2025 in “Tropical Journal of Natural Product Research” This study reports that a nanoemulsion was successfully formulated to deliver Moringa oleifera seed oil, which contains oleic acid and other fatty acids, and may serve as a promising dosage form for hair growth treatments.
May 2023 in “Pharma innovation” This review discusses PUFA-rich oil seeds and microencapsulation techniques but reports no new clinical results; the authors highlight microencapsulation as a promising method to protect PUFAs from oxidation.
September 2025 in “International Journal of Pharmaceutics and Drug Analysis” This study discusses ethosomes, which are lipid-based vesicular carriers that improve drug penetration into the skin due to their high ethanol content, highlighting their benefits in drug delivery despite stability issues like phospholipid oxidation and vesicle fusion during storage.
August 2025 in “International Journal of Pharmaceutical Sciences and Nanotechnology” This study formulated a minoxidil nanoemulgel with improved solubilization and skin penetration, demonstrating a high entrapment efficiency and sustained drug release in vitro, which suggests potential improvements in treating androgenetic alopecia compared to conventional formulations.
June 2021 in “Zenodo (CERN European Organization for Nuclear Research)” This study evaluated the stability and capillary growth-stimulating activity of emulsions made with natural plant extracts and oils in vivo on guinea pigs, finding that specific hydrophilic/lipophilic balance and globule size contribute to a stable and effective formulation.
44 citations
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November 2012 in “International journal of nanomedicine” This study found that silicone oil-in-water nanoemulsions using nonionic surfactants can enhance silicone oil absorption on hair, suggesting a promising method for hair care applications.
May 2004 in “International Journal of Cosmetic Science” This study suggests that selecting and controlling emollient systems can regulate the skin penetration of active ingredients in cosmetic formulations, impacting their efficacy.
December 2023 in “Biological & pharmaceutical bulletin” This study found that combining lecithin reverse wormlike micelles with isopropyl myristate enhanced the skin permeability of a model hydrophilic drug, facilitated by interactions with sebum in hair follicles.
This study developed a co-design framework using finite element analysis to optimize bubble microneedles, achieving controlled tip separation and effective drug delivery through the skin and mucosa while maintaining insertion strength.