Transethosomes: A Breakthrough System for Transdermal and Topical Drug Delivery

The document discusses the potential of transethosomes, a lipid-based nano-system, in transdermal and topical drug delivery. The stratum corneum, the outermost layer of the skin, often poses a significant barrier to drug delivery. Transethosomes, however, can permeate this rigid network due to their unique composition of phospholipids, ethanol, edge activator, and water. Ethanol provides softness, while the edge activator enhances permeation by providing elasticity, enabling drug molecules to be delivered into the bloodstream. This non-invasive technique can be used as a carrier for various drugs, including NSAID, anticancer, antifungal, and antihypertensive drugs.