A Review on Ethosomes Promising as Novel Drug Delivery Systems
September 2025
in “
International Journal of Pharmaceutics and Drug Analysis
”
New to Ethanol? There is a guide in the encyclopedia. Read the guide → Studysummary This study discusses ethosomes, which are lipid-based vesicular carriers that improve drug penetration into the skin due to their high ethanol content, highlighting their benefits in drug delivery despite stability issues like phospholipid oxidation and vesicle fusion during storage.
Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
Ethosomes are innovative lipid-based carriers that enhance drug penetration through the skin due to their high ethanol content, making them effective for delivering both hydrophilic and lipophilic drugs via topical or transdermal routes. They offer advantages such as improved skin penetration, flexibility in drug loading, and biocompatibility. However, challenges like vesicle stability, including phospholipid oxidation and vesicle fusion during storage, remain. Various assessment techniques are employed to ensure the quality, effectiveness, and safety of ethosomal formulations as drug delivery systems.
