Emulsion Formulation Assays Based on Natural Substances Stimulating Hair Growth and Evaluation of Its Biological Activity

June 2021 in “ Zenodo (CERN European Organization for Nuclear Research) ”

Emery Kalonda Mutombo, Marsi Mbayo Kitambala, Victor Ngambi Nyambi, Joseph Mbayo Mukala, Evodie Numbi Wa Ilunga, Jean-Baptiste Kalonji Ndumba, Kahumba Byanga Joseph, Jean-Baptiste Lumbu Simbi

emulsion formulation natural substances hair growth stimulation Hibiscus rosa-sinensis Cannabis sativa seed oil Ricinus communis oil Olea europaea oil beeswax Hydrophilic/Lipophilic Balance capillary growth stimulation hibiscus hemp seed oil castor oil olive oil

TLDR Natural substance emulsions can effectively stimulate hair growth.

This study investigated the formulation of stable water-oil emulsions using natural substances for hair growth stimulation. Emulsions were prepared with extracts from Hibiscus rosa-sinensis L., Cannabis sativa L. seed oil, Ricinus communis L. oil, Olea europaea oil, and beeswax, and tested in vivo on Cavia porcellus L. for 28 days. The optimal emulsion, with a 4/6 water-oil ratio, a Hydrophilic/Lipophilic Balance (HLB) of 7, and an average globule size of 2.57 ± 1.91 μm, demonstrated good stability and capillary growth stimulation. The study concluded that emulsion stability is influenced by the hydrophilic/lipophilic balance, globule size uniformity, and hydrophilic/lipophilic ratio.

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