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Optimization of LC Method for the Determination of Testosterone and Epitestosterone in Urine Samples for Biomedical and Anti-Doping Research

research Optimization of LC method for the determination of testosterone and epitestosterone in urine samples in view of biomedical studies and anti-doping research studies

21 citations , November 2010 in “Talanta”

This study reported the development of a novel and reliable liquid chromatographic method to measure testosterone and epitestosterone in human urine, offering sensitive detection for doping control.

Green Formulation of Spironolactone Loaded Chitosan Coated Nano Lipid Carrier for Treatment of Acne Vulgaris: A Randomized Double-Blind Clinical Trial

research Green formulation of spironolactone loaded chitosan coated nano lipid carrier for treatment of acne vulgaris: a randomized double-blind clinical trial

8 citations , September 2023 in “Advanced Pharmaceutical Bulletin”

In a double-blind clinical trial, this study found that a gel containing chitosan-coated spironolactone nanoparticles effectively reduced acne lesions over 8 weeks without adverse skin effects, suggesting potential for enhanced acne treatment through targeted skin delivery.

research Silicones as conditioning agents in shampoos

5 citations , January 1992

This study found that dimethicone with high molecular weight improved hair surface characteristics, while dimethicone copolyol and amodimethicone enhanced manageability by reducing friction or aiding styling on damaged hair.

research Emulsion formulation assays based on natural substances stimulating the hair growth and evaluation of its biological activity

June 2021 in “Zenodo (CERN European Organization for Nuclear Research)”

This study evaluated the stability and capillary growth-stimulating activity of emulsions made with natural plant extracts and oils in vivo on guinea pigs, finding that specific hydrophilic/lipophilic balance and globule size contribute to a stable and effective formulation.

Emulsion Formulation Assays Based on Natural Substances Stimulating Hair Growth and Evaluation of Its Biological Activity

research Emulsion formulation assays based on natural substances stimulating the hair growth and evaluation of its biological activity

June 2021 in “World Journal Of Advanced Research and Reviews”

In this study, researchers evaluated emulsions made with natural plant extracts and oils on guinea pigs, finding that a specific hydrophilic/lipophilic balance and globule size led to a stable emulsion and stimulated hair growth.

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community Jxl069 (pp405 api) week 8 update

205 upvotes 1 year ago

The user shared minimal results from using JXL-069 for hair loss, noting a slight lengthening of vellus hairs and plans to switch to a prodrug variant due to limited effectiveness. They also mentioned using finasteride and minoxidil, which have plateaued in results.

community Why is dutasteride's volume of distribution so much bigger than finasteride? Is it more lipophilic and crosses barriers better?

23 upvotes 1 year ago

Dutasteride has a larger volume of distribution than finasteride due to its lipophilic nature, allowing it to concentrate in hydrophobic areas and making it difficult to excrete. A user experiencing hair loss has been using oral finasteride for 10 months with minimal regrowth and is considering switching to dutasteride or adding oral minoxidil.

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