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This review discusses lipid-polymer hybrid nanoparticles for dermatological applications, outlining their structural and formulation advancements, but reports no new clinical results and calls for further research on their therapeutic potential.

This study found that using Labrasol® in phospholipid vesicle formulations improved minoxidil's skin delivery and local accumulation, showing potential for treating hair growth disorders.

This study demonstrated that a new topical treatment using ketotifen-loaded microneedles, designed for prolonged release, significantly reduced inflammatory markers in an animal model of allergic conjunctivitis, suggesting enhanced therapeutic delivery and sustained ocular benefits.

This study concluded that niosomes could effectively serve as stable carriers for topical aminexil delivery, showing promising stability and a slow, biphasic release profile in laboratory settings.

In this study, TyroSpheres were used to encapsulate adapalene, increasing its solubility and enhancing skin distribution while reducing irritancy compared to a commercial formulation, indicating promise for acne treatment in ex vivo and in vitro settings.

This review highlights the potential of olive mill wastewater as a sustainable source of cosmeceutical ingredients with antioxidant, anti-inflammatory, and dermatological benefits but reports no new clinical findings.

This study developed and tested Bicalutamide-loaded lipid vesicles in dissolving microarray patches for topical application, finding that they effectively deliver Bicalutamide through murine skin while maintaining a favorable safety profile, suggesting potential to improve treatments for androgenetic alopecia.

In this study, researchers developed vegan exosome-like vesicles from microalgae that mimic mammalian exosomes, demonstrating promising in vitro, ex vivo, and clinical effects such as improved wrinkle depth and elasticity, making them a potential alternative in cosmetic applications.

This study developed a personalized microneedle that delivers finasteride directly to the skin, facilitating a sustained release and potentially reducing side effects associated with oral administration.

This study found that methyl nonanoate and methyl caprate significantly enhanced the skin penetration of minoxidil compared to solutions with other common enhancers like Azone, DMSO, or DEET.

This review discusses the potential of microneedles as a pain-free drug delivery method that improves medication distribution while addressing issues associated with traditional transdermal formulations.

This review discusses the advantages, applications, and current trends of dissolving microneedles for drug delivery across various therapeutic areas and reports no new clinical results.

This study evaluated niosome-based gels for delivering salicylic acid topically to treat acne vulgaris and found that the formulation SANG5, using Carbopol 940 and nutmeg oil, demonstrated the best drug release profile.

In this study, solid lipid microparticles loaded with lidocaine hydrochloride were developed to effectively deliver pain relief and antimicrobial benefits for wound management, demonstrated by testing with bioengineered skin substitutes and showing effectiveness against common wound-infecting bacteria.

This study found that using 2-hydroxypropyl-ß-cyclodextrin (HP-ß-CD) to encapsulate minoxidil can create a stable aqueous solution, potentially replacing the need for organic solvents in topical treatments for androgenic alopecia.

This study found that nanoparticles containing minoxidil and betamethasone improved drug delivery to hair follicles, with lipidic nanoparticles significantly enhancing minoxidil and betamethasone penetration compared to control, making them a promising option for alopecia areata treatment with reduced side effects.

This study used advanced optical imaging techniques to investigate nanoparticle and dye penetration in human skin, finding that nanoparticles mainly resided in the stratum corneum and accumulated in skin folds and hair follicles, while highlighting that sunscreen-based nanoparticles appear unlikely to pose safety concerns.

This study reported that invasomes, utilizing limonene as a component, enhanced the transdermal permeation of finasteride by over 21 times, indicating their potential as a novel drug delivery system.

This review discusses the potential of extracellular vesicles from various sources for skin rejuvenation and cosmetic use, noting promising results, especially with mesenchymal stem cell-derived vesicles, but reports no new clinical results.

This study found that finasteride delivered through dissolving microneedles enhanced skin drug permeation compared to films, suggesting potential for improved androgenetic alopecia treatment with fewer side effects.

This study developed a new melanocyte cultivation medium without chemical mitogens, melanogenesis enhancers, or bovine products, demonstrating successful proliferation and melanotic differentiation of human melanocytes from hair follicles.

This study proposes a metal-organic gel-encapsulated microneedle system with antibacterial, anti-inflammatory, and pro-angiogenic properties for treating infected wounds, demonstrating potential for precise and adaptive management by targeting various stages of wound healing.

This review discusses how liposomes and niosomes can enhance drug penetration in topical delivery systems and emphasizes the importance of their specific composition, size, and type, but it reports no new results.

In this study, researchers formulated a nanosuspension of kenikir leaf extract that meets physical criteria and exhibits cytotoxic activity against MCF-7 breast cancer cells.

This review highlights that herbal nanoemulgel-based hair dyes, enriched with natural ingredients, improve dye penetration and retention and offer additional hair and scalp benefits compared to conventional dyes, although further research is necessary to verify their safety and efficacy for long-term use.

This study found that electroosmotic flow through hair follicles significantly contributes to solution flow during iontophoresis in hairless mouse skin.

This study involved formulating an invasome gel loaded with clotrimazole for treating fungal infections and assessed its various properties like spreadability and in vitro drug diffusion.

This review discusses various types of microneedles and their potential to expand the range of drugs delivered via the skin, but reports no new clinical results.

This study found that a combination of 5% DMSO and BSA minimizes toxic effects on the cytogenetic stability of dermal papilla cells during cryopreservation.

In this study, extracts from Chenopodium quinoa, Glycine max, and Malpighia emarginata demonstrated stability, low toxicity, and effective cleaning potential as surfactants in shampoo formulations, showing performance similar to or better than commercial shampoos in terms of surface and interfacial tension and sebum removal.