August 2018 in “Farmatsevtychnyĭ zhurnal” This study developed an emulgel containing Saw Palmetto extract and Sophora Japonica tincture for treating androgenic alopecia, optimizing its preparation process to enhance dispersion and rheological properties.
38 citations
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March 2015 in “Journal of controlled release” This study found that transfollicular delivery using surfactant-based nanoparticles significantly enhanced antigen stability and immune response compared to other delivery methods, especially when combined with an adjuvant.
2 citations
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February 2022 in “Journal of Pharmacy and Pharmacology” In this study, two methotrexate-loaded liquid crystal formulations for topical application showed immunomodulatory effects and induced skin changes in mice with imiquimod-induced psoriasis.
5 citations
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January 2017 in “Chalmers Publication Library (Chalmers University of Technology)” In this study, cubosome and hexosome carriers with antimicrobial peptides showed varied efficacy, with cubosomes protecting peptides from degradation and enhancing bactericidal effects in some cases, while hexosomes lacked antimicrobial activity.
1 citations
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February 2023 in “International journal of research - granthaalayah” This study reports that electromagnetic energy from a hydrocolloid wound dressing paste adversely affected human skin lipid droplets in vitro, but the implications, including potential cancer links, are unknown.
2 citations
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November 2024 in “International Journal of Pharmaceutics X” In this study, desmopressin-loaded elastic liposomes (ODEL1) showed improved permeation and drug deposition across rat skin by altering the skin's cohesive energies and causing reversible changes on its surface.
65 citations
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March 2022 in “Molecules” This study examines the role of nanotechnology in cosmetics, highlighting its benefits in improving ingredient solubility and stability, but also noting challenges such as cost, shelf life, and safety concerns, along with regulatory complexities, particularly in harmonizing global legislation.
August 2025 in “MedComm – Biomaterials and Applications” This review highlights recent advances in liposome-based transdermal drug delivery systems, emphasizing their potential to improve drug penetration for both skin and systemic diseases while discussing the challenges and future directions in this field.
June 2025 in “Medical academic journal” The study found that hybrid nanoparticles incorporating exosomes with cationic liposomes 2X3-DOPE significantly improved the delivery of both messenger RNA and small interfering RNA to rat cardiac mesenchymal stem cells in vitro, achieving up to 100% transfection efficiency for small interfering RNA.
July 2026 in “Materials Today Bio” This study demonstrated that in a mouse melanoma wound model, the MQ Microneedles effectively managed ROS levels to inhibit tumor growth and promote wound healing through light-controlled release.
2 citations
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July 2020 in “Journal of Drug Delivery Science and Technology” In this study, forming inclusion complexes of Finasteride and poly (ethylene glycol) resulted in significantly improved solubility and dissolution rates, suggesting a promising new solid form for enhanced drug release.
December 2021 in “The Korean Society of Beauty and Art” In this study, a microneedle patch system using pullulan as a polymer was found to efficiently deliver finasteride, promising convenience and effectiveness in treating hair loss.
August 2022 in “Frontiers in Pharmacology” Ultrasound can improve targeted drug delivery, making treatments more effective with fewer side effects.
January 2026 in “Journal of Materials Chemistry B” In this study, researchers developed a delivery system using a deep eutectic solvent to improve hydroxytyrosol absorption for hair regrowth, achieving over threefold greater skin penetration compared to aqueous solutions and demonstrating its effectiveness and biocompatibility in hair regrowth and ROS-scavenging tests.
January 2025 in “International Journal of Research and Innovation in Applied Science” This study aimed to enhance the skin penetration of minoxidil by encapsulating it in glycerosomal vesicles, offering a potential improvement in transdermal drug delivery for treating androgenetic alopecia. Results of the investigation were not reported.
March 2025 in “Asian Journal of Beauty and Cosmetology” This study found that microspicule cosmetics with low-molecular-weight peptide complexes significantly improved skin whitening, pore condition, and skin barrier function over four weeks compared to a non-microspicule formulation.
151 citations
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July 2011 in “Archives of Dermatological Research” This review discusses various strategies to enhance drug delivery through the skin barrier, highlighting liposomes as promising carriers for increased dermal concentrations in topical therapies, but reports no new research results.
7 citations
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January 2023 in “Biofabrication” This study developed microfluidic-assisted GelMA-MSC/HAD-EPC microspheres that efficiently generated hair follicles in nude mice, suggesting a promising strategy for advancing hair-regenerative medicine.
July 2026 in “Journal of Drug Delivery Science and Technology”
This study found that in an androgenetic alopecia mouse model, phospholipid-bile salt mixed micelles for topical Finasteride delivery improved hair regrowth and reduced systemic absorption compared to a hydroalcoholic solution, suggesting a safer and more effective treatment option.
14 citations
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April 2019 in “Saudi pharmaceutical journal” This study reported that microparticle-loaded emulsions containing caffeic acid achieved more homogeneous distribution and prolonged release in hair follicles, suggesting potential for effective folliculitis treatment.
July 2025 in “Ultrasound in Medicine & Biology” This study found that nanobubble-encapsulated diclofenac with ultrasound-targeted microbubble destruction (DNBs-UTMD) can enhance the anti-tumor efficacy of Doxil® by regulating the tumor immune microenvironment, improving drug uptake, and increasing T cell responses while reducing immune-suppressive cells in the process.
July 2013 in “Pharmaceutical Regulatory Affairs Open Access” Formulation F1 is the best for delivering finasteride effectively.
January 2023 in “Records of Pharmaceutical and Biomedical Sciences” This review discusses the advantages and properties of mucoadhesive buccal dosage forms and reports no new clinical findings; the authors emphasize the potential of spanlastics as flexible, biodegradable drug carriers.
8 citations
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August 2012 in “Clinical, cosmetic and investigational dermatology” In this study, Doublebase gel was more effective in maintaining and increasing skin hydration compared to Aqueous cream BP, with higher patient satisfaction and preference for future use.
October 2018 in “Annals of Reviews & Research” This open-access journal publishes innovative research articles across various fields but reports no new clinical results in this summary.
May 2026 in “Pharmacy Reports” This systematic review found that while green solvent- and natural excipient-based semisolid formulations often show promising efficacy and safety compared to conventional options, the evidence does not currently establish superior stability, highlighting a need for further research on long-term formulation quality.
33 citations
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June 1995 in “Journal of Pharmaceutical Sciences” This study found that minoxidil penetration through the skin increased with higher ethanol content and occlusion, with the highest penetration observed at 90% ethanol.
15 citations
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April 2023 in “Biology” This review discusses the characteristics, extraction strategies, and potential applications of plant and algal lipid droplets but reports no new empirical findings.
5 citations
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April 2021 in “Frontiers in Pharmacology” In this mouse study, the combination of minoxidil-coated lysozyme microbubbles and ultrasound significantly enhanced hair growth compared to minoxidil alone.