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Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Mice with LSS deficiency showed hair loss and cataracts, similar to humans, and can help in understanding and treating this condition.

Hair can indicate early signs of metabolic disorders, with issues like protein deficiency stopping hair growth.

Many infertile women with PCOS in Central Vietnam have metabolic or insulin resistance syndrome, with obesity and older age increasing the risk.

Some skin diseases and their treatments can negatively affect male fertility.

Postmenopausal women with hyperandrogenism didn't have better metabolic health even after their testosterone levels became normal.

IL6 is linked to higher risk of heart disease in people with a certain mouth condition.

Finasteride, a drug used for certain conditions, can cause serious side effects like sexual dysfunction, suicidal thoughts, and increased diabetes risk, and there's a need for more awareness and research about these effects.

Managing metabolic syndrome needs both lifestyle changes and medical treatments.

The document concludes that certain genetic mutations and dietary factors are involved in acne development, and treatments like isotretinoin and diet changes can help manage it.

Surgery to lower high testosterone in postmenopausal women with certain ovarian tumors doesn't significantly affect their metabolism.

Diabetes can lead to blindness and skin problems, and managing blood sugar and blood pressure is crucial to prevent these complications.

Some skin problems can be signs of diabetes or other metabolic diseases and recognizing them can help diagnose and treat these diseases early.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

Type 2 diabetes in youth is increasing, with high treatment failure rates and more severe than Type 1; certain drugs can lower lipid levels effectively with varying side effects, and apples may benefit heart health like statins but with fewer side effects.

Testosterone therapy improved physical and social health in a male with 49,XXXXY syndrome.

Researchers created a new mouse model for studying Citrullinemia Type I and similar conditions, showing symptoms and treatment responses like those in humans.

Genetic defects in the glucocorticoid receptor gene can cause conditions with abnormal sensitivity to stress hormones, and other factors may also affect this sensitivity.

Obesity is a major risk factor for insulin resistance in Taiwanese women with PCOS, which is also an independent risk factor for metabolic syndrome.

PCOS symptoms change with age; younger women have higher androgen levels and less metabolic issues, while older women face more metabolic challenges despite milder PCOS symptoms.

Taiwanese women with PCOS experience different symptoms based on age, with younger women facing more hormone imbalances and older women dealing with more metabolic issues.

Hair loss links to high blood pressure, high fat levels, and metabolic issues, suggesting early heart disease screening.

The document concludes that managing PCOS involves treating symptoms and reducing long-term metabolic risks, with lifestyle changes being important.

Skin health and diseases are closely linked to metabolic processes.

The conclusion is that obesity should be managed with a slow, balanced approach to diet and exercise, with medication and surgery as additional options, and education and access to care are important.

Understanding how acne develops in different diseases could lead to new treatments.

Central lipohypertrophy in HIV-infected women may lead to shorter eyelashes.

Metformin is less effective in men with early-onset hair loss.

Metreleptin treatment significantly improved metabolic health in a boy with congenital generalized lipodystrophy.

Understanding the genetics of rare inherited ichthyosis syndromes is key for better treatments and genetic counseling.