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Insulin resistance is not more common in idiopathic hirsutism patients than in healthy individuals.

Myo-inositol may be more effective than metformin for inducing ovulation in women with PCOS.

The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.

Vitamin D deficiency is common in people with certain types of hair loss, like alopecia areata and female pattern hair loss.

Certain small molecules can promote hair growth by activating a cellular cleanup process called autophagy.

Diagnosing PCOS in teenage girls is tricky and requires careful evaluation and management.

Anorexia Nervosa and Bulimia Nervosa are complex eating disorders with increasing incidence among young females, significant morbidity, and varying mortality rates, requiring more research for better treatment.

Testosterone replacement may help post-menopausal women with androgen insufficiency, but more research is needed on its benefits and risks.

Many pediatric epilepsy patients experience preventable severe adverse drug reactions, especially with certain medications and risk factors.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Non-surgical procedures can help reduce wrinkles and stimulate skin repair by understanding skin aging at the molecular level.

Gender-affirming hormone therapy improves physical performance in trans men to the level of cisgender men, while in trans women, it increases fat mass and decreases muscle mass, with no advantage in physical performance after 2 years.

Men and women respond differently to drugs for COVID-19, high cholesterol, and diabetes, which suggests a need for personalized treatments.

The document concludes that certain genetic mutations and dietary factors are involved in acne development, and treatments like isotretinoin and diet changes can help manage it.

The conclusion is that the best initial treatment for hirsutism is usually oral contraceptives, with the addition of antiandrogens or insulin sensitizers if needed, and topical eflornithine or laser treatments as supplementary options.

Testosterone replacement may help postmenopausal women with sexual function and bone density, but suitable treatments are limited.

Melatonin improved mental health and metabolism in women with PCOS.

Women with PCOS have higher xanthine oxidase activity linked to inflammation and heart disease risks.

Certain medications can impact metabolic syndrome, with some improving conditions like high blood sugar and others having no effect.

Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.

Losing weight and eating better are key to managing metabolic syndrome and its related conditions.

Mood stabilizers like lithium and anticonvulsants have side effects that can lead to patients stopping their medication, and managing these effects is important for treatment adherence.

Testosterone replacement may improve sexual desire and bone health in women with low androgen levels, but more research is needed on its long-term safety.

Natural products may help treat skin inflammation from abnormal adrenal hormones.

Mozuku seaweed fucoidan can inhibit harmful skin bacteria growth.

Finasteride raises suicide-linked aggression and stops clozapine's positive effects in schizophrenia animals.

PPARγ is crucial for skin health but can have both beneficial and harmful effects.

Long-term use of finasteride and dutasteride can cause serious health issues like diabetes and liver problems.

Probiotics show promise for health benefits but need more research to understand how they work.

The document concludes that various medications and treatments can have significant, sometimes adverse, effects on health outcomes.