August 2024 in “Bioimpacts” Kopexil is an effective and safe hair growth treatment.
218 citations,
October 2013 in “Proceedings of the National Academy of Sciences of the United States of America” Mice lacking the PPARγ gene in their fat cells had almost no fat tissue, severe metabolic problems, and abnormal development of other fat-related tissues.
13 citations,
July 2019 in “Toxicology research” Ethanamizuril is safe for rats at 20 mg/kg feed, but higher doses cause hair loss, organ changes, and liver, kidney, and lung damage.
11 citations,
January 2017 in “Journal of Endocrinology/Journal of endocrinology” Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.
18 citations,
October 2013 in “EFSA Journal” Coriander seed oil is safe for healthy adults at up to 600 mg per day.
12 citations,
January 2016 in “Journal of clinical biochemistry and nutrition” Deferasirox combined with sorafenib reduces liver cancer risk and lessens treatment side effects.
Diphenyl cresyl phosphate has low toxicity but can harm the liver, kidneys, adrenal glands, and testicles at high doses.
158 citations,
May 1968 in “The journal of nutrition/The Journal of nutrition” Zinc is crucial for growth and health in rats.
20 citations,
May 1985 in “British journal of nutrition” Dietary essential fatty acids improved skin and hair conditions and partially corrected fat composition in diabetic mice.
3 citations,
March 2017 in “Regulatory toxicology and pharmacology” Aleglitazar and its major metabolite are safe enough to proceed to Phase 3 clinical trials.
21 citations,
July 2020 in “Stem Cell Research & Therapy” Fat stem cells from diabetic mice can still help heal wounds.
19 citations,
September 2010 in “The American journal of pathology” High glucocorticoids cause pancreatic malfunction and malabsorption, reversible with enzyme supplements.
17 citations,
April 2021 in “Clinical Phytoscience” Chitrak is a medicinal plant with health benefits like fighting microbes, reducing inflammation, and promoting hair growth, but it can be toxic and needs more research.
December 2023 in “Journal of nutritional science and vitaminology” A zinc-deficient diet stunted growth and affected organs in mice, with C57BL/6J mice showing more severe symptoms.
118 citations,
May 2003 in “Toxicological Sciences” Exposure to finasteride in the womb caused lasting reproductive issues in male rats.
1 citations,
May 2023 in “Frontiers in Pharmacology” Millet seed oil may help hair grow by activating certain cell growth signals.
Justicia procumbens extract may help prevent hair loss and improve hair thickness and shine in a type of hair loss condition.
18 citations,
September 2011 in “Livestock science” Maternal Nano-Se supplements improve fetal hair follicle development in cashmere goats.
14 citations,
August 2016 in “Journal of nanomedicine research” Zinc oxide nanoparticle biscuits improved growth and health in zinc-deficient rats without toxicity.
43 citations,
January 1977 in “Toxicology and Applied Pharmacology” Minoxidil is mostly safe, but high doses can cause electrolyte imbalances and heart issues in dogs.
35 citations,
August 1980 in “Circulation” Minoxidil may cause heart issues in animals and humans.
24 citations,
July 1980 in “Journal of Toxicology and Environmental Health” High doses of norethindrone acetate in rats caused various organ changes but didn't significantly increase tumor rates.
20 citations,
September 2019 in “South African Journal of Botany” Teucrium polium extracts are non-toxic and effectively speed up wound healing.
4 citations,
February 2022 in “PeerJ” Hair follicle stem cell transplants can reverse liver cirrhosis by blocking harmful cell activation.
2 citations,
April 2021 in “Asian pacific Journal of Tropical Biomedicine” Origanum vulgare leaf extract reduces liver and kidney damage caused by finasteride in mice.
14 citations,
August 2019 in “BioMed Research International” Belly fat is the main predictor of nonalcoholic fatty liver disease in both women with Polycystic ovary syndrome and healthy women.
5 citations,
January 2016 in “Asian pacific Journal of Tropical Biomedicine” Phthirusa pyrifolia extract may lower testosterone and harm male rat reproduction without damaging the liver or kidneys.
December 2020 in “Nigerian journal of animal production” Dexamethasone can cause diabetes in rats, and Annona muricata bark extract may help lower blood sugar.
55 citations,
July 1999 in “Clinics in Sports Medicine” Athletes use steroids to enhance performance despite health risks and legal issues, and education on their dangers is needed.
31 citations,
January 2017 in “Advances in Experimental Medicine and Biology” Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.