Scientific Opinion on the Safety of Coriander Seed Oil as a Novel Food Ingredient

The EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) evaluated the safety of coriander seed oil (CSO) as a novel food ingredient. The primary fatty acid in CSO is petroselinic acid (PA). The oil is intended for use as a food supplement for healthy adults at a maximum of 600 mg per day. Studies showed no genotoxicity concerns, but high doses in rats led to increased liver weight and fat infiltration. A subchronic study identified a NOAEL of 450 mg/kg bw per day in rats, which is significantly higher than the proposed use level. A human study found no adverse effects at the proposed use level over six months. The Panel concluded that CSO is safe under the proposed uses and levels.