Kopexil vs Minoxidil: In Vivo Comparative Study on Hair Growth, Hair Growth Promoting Factors and Toxicity

    August 2024 in “ Bioimpacts ”
    Sina Jalilzadeh, Nariman Maroofpour, Farnaz Monajjemzadeh
    Studysummary In this study on mice, a hydro-alcoholic solution containing kopexil significantly enhanced hair growth and increased hair-promoting factors without causing notable liver or kidney toxicity compared to minoxidil.
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    Research cited in this study 27

    1. Comparing Current Therapeutic Modalities of Androgenic Alopecia: A Literature Review of Clinical Trials Cureus · 2023
    2. Use of 5-Alpha Reductase Inhibitors in Dermatology: A Narrative Review Dermatology and Therapy · 2023
    3. Overview Of Alopecia Areata For Managed Care And Payer Stakeholders In The United States Journal of managed care & specialty pharmacy · 2023
    4. The Inflammatory Component of Androgenetic Alopecia Journal of The American Academy of Dermatology · 2021
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    7. A Systematic Review on Topical Marketed Formulations, Natural Products, and Oral Supplements to Prevent Androgenic Alopecia Natural Products and Bioprospecting · 2020
    8. Prevention and Treatment of Chemotherapy-Induced Alopecia Dermatology practical & conceptual · 2020
    9. Subjects With Mild Alopecia Benefit From Aminexil Clinical 5: Results of a Large International Observational Study IRIS UNIMORE (University of Modena and Reggio Emilia) · 2020
    10. Efficacy of Different Concentrations of Intralesional Triamcinolone Acetonide for Alopecia Areata: A Systematic Review and Meta-Analysis Journal of the American Academy of Dermatology · 2019
    11. Chemotherapy-Induced Hair Loss: The Use of Biomarkers for Predicting Alopecic Severity and Treatment Efficacy Biomarker Insights · 2019
    12. Alopecia Areata: A Multifactorial Autoimmune Condition Journal of autoimmunity · 2018
    13. Alopecia Areata: Overview and Insights from January 2018 Journal of The American Academy of Dermatology · 2017
    14. Alopecia Areata: A Comprehensive Review of Pathogenesis and Management Clinical Reviews in Allergy & Immunology · 2017
    15. The Effectiveness of Treatments for Androgenetic Alopecia: A Systematic Review and Meta-Analysis Journal of The American Academy of Dermatology · 2017
    16. Interventions for Female Pattern Hair Loss The Cochrane library · 2016
    17. Hair Loss And Regeneration Performed On Animal Models Medicine and Pharmacy Reports · 2015
    18. Epidemiology and Burden of Alopecia Areata: A Systematic Review Clinical, Cosmetic and Investigational Dermatology · 2015
    19. Alopecia Areata Is Driven by Cytotoxic T Lymphocytes and Is Reversed by JAK Inhibition Nature medicine · 2014
    20. An Overview of Alopecias Cold Spring Harbor Perspectives in Medicine · 2014
    21. Platelet-Rich Plasma in Androgenic Alopecia: Myth or Effective Tool Journal of Cutaneous and Aesthetic Surgery · 2014
    22. Randomized Comparison of Topical Betamethasone Valerate Foam, Intralesional Triamcinolone Acetonide, and Tacrolimus Ointment in Management of Localized Alopecia Areata International journal of trichology · 2011
    23. Interventions for Androgenic Alopecia in Women Cochrane Database of Systematic Reviews · 2009
    24. Efficacy And Safety Of A New Clobetasol Propionate 0.05% Foam In Alopecia Areata: A Randomized, Double-Blind Placebo-Controlled Trial Journal of the European Academy of Dermatology and Venereology · 2006
    25. A Comparison of the Efficacy, Relapse Rate, and Side Effects Among Three Modalities of Systemic Corticosteroid Therapy for Alopecia Areata Dermatology · 2006
    26. Approach to the Adult Female Patient with Diffuse Nonscarring Alopecia Journal of The American Academy of Dermatology · 2002
    27. Androgenetic Alopecia: Treatments and Efficacy Dermatologic Clinics · 2000

    Related research 10

    1. Role Of Oral Minoxidil In The Treatment Of Androgenetic Alopecia Cosmoderma · 2024
    2. Deterioration of Scalp Environment by Exogenous Factors and Its Influence on Hair Growth Promoting Effect of Minoxidil The Pharmaceutical Society of Japan · 2020
    3. 5% Minoxidil: Treatment for Female Pattern Hair Loss PubMed · 2015
    4. A Study on Effects of Water-Soluble Minoxidil on Hair Growth in C57BL/6 Mice Strait Pharmaceutical Journal · 2007
    5. Minoxidil: Mechanisms of Action on Hair Growth British Journal of Dermatology · 2004
    6. Effect of Minoxidil on Hair Growth in Androgenic Alopecia in Women PubMed · 2002
    7. Towards a Molecular Understanding of Hair Loss and Its Treatment Trends in Molecular Medicine · 2001
    8. KF19418, A New Compound for Hair Growth Promotion in Vitro and in Vivo Mouse Models Journal of Dermatological Science · 2001
    9. Treatment of Hair Loss The New England Journal of Medicine · 1999
    10. The Use of Minoxidil to Prevent Alopecia During Chemotherapy for Gynecologic Malignancies PubMed · 1991