Kopexil vs Minoxidil: In Vivo Comparative Study on Hair Growth, Hair Growth Promoting Factors and Toxicity

    August 2024 in “ Bioimpacts
    Sina Jalilzadeh, Nariman Maroofpour, Farnaz Monajjemzadeh
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    TLDR Kopexil is an effective and safe hair growth treatment.
    This study compared the effects of a 5% hydro-alcoholic solution containing kopexil to minoxidil on hair growth in mice over 28 days. The kopexil group showed significant improvements in hair weight, follicle count, percentage of anagen hair, and overall hair growth compared to the minoxidil group. Western blot analysis indicated higher levels of hair growth-promoting factors (HGF and VEGF) in the kopexil-treated group. Toxicity tests revealed no significant differences in liver and kidney weights or morphological changes among the groups. The findings suggest that kopexil is an effective and safe hair growth stimulator, making it a viable treatment option for hair loss.
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