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Heavy duty finasteride that comes with higher risks, but scalp injections seem safe and are gaining popularity
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learn Cyproterone
a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor
learn GT20029
research compound made to degrade androgen receptors in scalp
Research
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research 28-Day Repeated Dose Toxicity and Toxicokinetics Study on Dihydroartemisinin in SD Rats
High doses of dihydroartemisinin caused reversible liver toxicity in rats, with females more affected than males.
research Kopexil vs Minoxidil: In Vivo Comparative Study on Hair Growth, Hair Growth Promoting Factors and Toxicity
Kopexil is an effective and safe hair growth treatment.
research Lipoatrophy and Severe Metabolic Disturbance in Mice with Fat-Specific Deletion of PPARγ
Mice lacking the PPARγ gene in their fat cells had almost no fat tissue, severe metabolic problems, and abnormal development of other fat-related tissues.
research Acute and 30-Day Oral Toxicity Studies of a Novel Coccidiostat – Ethanamizuril
Ethanamizuril is safe for rats at 20 mg/kg feed, but higher doses cause hair loss, organ changes, and liver, kidney, and lung damage.
research Metabolic Dysfunction in Female Mice with Disruption of 5α-Reductase 1
Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.
Community Join
5 / 1000+ resultscommunity Will my liver get destroyed long term on this stack ??
A user is considering a long-term hair loss treatment stack including Dutasteride, Finasteride, and oral Minoxidil, and is concerned about potential liver damage. Some responses suggest the stack is excessive, while others believe it's not harmful to the liver, but recommend regular blood work to monitor health.
community How Dangerous is Oral Min Really?
Oral minoxidil is generally effective for hair loss but may cause side effects like heart palpitations and facial puffiness. Users highlight the importance of monitoring blood pressure due to potential cardiovascular risks.
community Hormonal panel after 1 year of treatment - DHT levels doubled!!
A 27-year-old man shared his hormonal panel results after one year of taking finasteride 1mg/day for hair loss, showing his DHT levels nearly doubled. He reported stabilized hair loss with mild side effects that resolved, and he is considering a hair transplant but is concerned about the increased DHT levels and potential treatment options.
community Methods Of Staying Safe On Ru58841 - My 2 Cents
RU58841 is used topically to prevent hair loss by blocking DHT, with suggestions to drink grapefruit juice, take breaks, avoid microneedling, and use lower concentrations to reduce side effects. Users discuss applying it at night to minimize systemic absorption.
community I’ve been on dutesteride and oral minoxidil for two years now and I’ve only lost ground… 25m What should I do?
A user on dutasteride and oral minoxidil for two years has experienced worsening hair loss and an itchy scalp. Suggestions include increasing medication doses, trying other treatments like RU58841, getting a scalp biopsy, and addressing potential inflammation through diet and topical treatments.